{"id":"W2993192776","doi":"10.7554/elife.50850","title":"Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis","year":2019,"lang":"en","type":"article","venue":"eLife","topic":"Cell Image Analysis Techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"National Research Foundation of Korea; Canadian Institutes of Health Research; Ministry of Science, ICT and Future Planning","keywords":"Phosphorylation; Kinome; Biology; Morphogenesis; Cell biology; Protein phosphorylation; Neuroscience; Protein kinase A; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001638869,0.0003559031,0.0002018752,0.0003051522,0.0002855588,0.000356916,0.0001865944,0.000199219,0.001688155],"category_scores_gemma":[0.0001862489,0.0001928579,0.0003619465,0.000154686,0.0001792972,0.0003644809,0.000265616,0.0005517624,0.00052615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004596892,"about_ca_system_score_gemma":0.0002833509,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005464199,"about_ca_topic_score_gemma":0.001847973,"domain_scores_codex":[0.9998529,0.00001216501,0.00001411204,0.0000501631,0.00003958099,0.00003110139],"domain_scores_gemma":[0.999895,0.00001128617,0.00004126632,0.000009484376,0.00001359948,0.00002941317],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008547644,0.000010161,0.0007041343,0.00004551923,0.000007774807,0.000126685,0.0000136648,0.00006198684,0.9967464,0.0001680464,0.000080394,0.001949731],"study_design_scores_gemma":[0.00001690758,0.00004915254,0.02632546,0.000007965757,0.00001774466,0.0009334467,0.00003862036,0.001291582,0.9680238,0.0001899543,0.003095,0.00001024062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9782116,0.002995653,0.01427025,0.0003213954,0.00006586644,0.00003237294,0.0007923468,0.0002291243,0.003081243],"genre_scores_gemma":[0.9836417,0.001389163,0.01028105,0.00007525166,0.00001362861,0.00004280638,0.00104717,0.00004410383,0.003465145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001688155,"threshold_uncertainty_score":0.005647421,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01597371339445706,"score_gpt":0.298413060271217,"score_spread":0.2824393468767599,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}