{"id":"W2993246221","doi":"10.1016/j.celrep.2019.11.010","title":"Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation","year":2019,"lang":"en","type":"article","venue":"Cell Reports","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"National Center for Research Resources; Children’s Hospital of Wisconsin Research Institute; Roy J. and Lucille A. Carver College of Medicine, University of Iowa; National Institute of Allergy and Infectious Diseases; National Eye Institute; Holden Comprehensive Cancer Center, University of Iowa; Comprehensive Cancer Center, City of Hope; National Cancer Institute; National Institutes of Health; Center for Outcomes Research and Evaluation, Yale School of Medicine; National Institute of Diabetes and Digestive and Kidney Diseases; University of Iowa; American Association of Immunologists","keywords":"Nod; Pathogenesis; Inflammation; NOD mice; Type 1 diabetes; Immunology; Interleukin; Biology; Diabetes mellitus; Type 2 diabetes; Medicine; Cytokine; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001527139,0.0008376481,0.0003019227,0.0007060969,0.0002380843,0.000368518,0.0002812658,0.000346869,0.003614998],"category_scores_gemma":[0.0001925803,0.0002584846,0.00037558,0.0002592106,0.0005367929,0.0001699604,0.0004381095,0.0006608212,0.001154078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002564396,"about_ca_system_score_gemma":0.0004081604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003116668,"about_ca_topic_score_gemma":0.0005576698,"domain_scores_codex":[0.9997335,0.00006368865,0.00003350131,0.00004529028,0.00007330846,0.00005072276],"domain_scores_gemma":[0.9994245,0.00005541476,0.0002525802,0.00005258616,0.0000213798,0.0001936092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005373374,0.00008035157,0.000836913,0.00004639473,0.00001257101,0.0003901098,0.00001531166,0.0001304245,0.9962185,0.0003120996,0.0001138631,0.00130606],"study_design_scores_gemma":[0.0002656284,0.001108192,0.04903385,0.00006390451,0.00008463639,0.005209041,0.0001716227,0.001775407,0.9264622,0.0006220757,0.01516707,0.0000364415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917803,0.001170716,0.002379433,0.0002260279,0.00006792583,0.00003265043,0.001557437,0.000219786,0.00256555],"genre_scores_gemma":[0.9916764,0.0008260167,0.001981981,0.00005009951,0.0000211984,0.0000429564,0.001738959,0.000104327,0.00355806],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003614998,"threshold_uncertainty_score":0.01209337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004788494487785856,"score_gpt":0.2106804531868289,"score_spread":0.2058919586990431,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}