{"id":"W2993286963","doi":"","title":"LIPASE-CATALYZED ENANTIOSELECTIVE ESTERIFICATION OF KETOPROFEN IN ORGANIC MEDIA","year":2000,"lang":"en","type":"article","venue":"","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"CAE (Canada)","funders":"","keywords":"Ketoprofen; Lipase; Chemistry; Enantiomer; Catalysis; Cyclohexane; Enantioselective synthesis; Kinetic resolution; Incubation; Enzyme; Organic chemistry; Chromatography; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001063446,0.00006662471,0.00009551029,0.00003989507,0.0000129086,0.000004804135,0.00008690804,0.00008118106,0.000591795],"category_scores_gemma":[0.00005432101,0.00005924749,0.00003254837,0.0001998519,0.00002744244,0.000004597166,0.00001342169,0.00002863253,0.0000176541],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007761193,"about_ca_system_score_gemma":0.00003681913,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002590415,"about_ca_topic_score_gemma":0.0001946457,"domain_scores_codex":[0.9994425,0.0000310705,0.0001906795,0.0001852354,0.00005983455,0.00009068646],"domain_scores_gemma":[0.9996579,0.000006980729,0.0000439441,0.0002138821,0.00005594093,0.00002133728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003148819,0.00006667771,0.002183942,0.000005540568,0.000009882195,1.341839e-7,0.0001186795,0.00001210083,0.9926021,0.00005475658,0.0001143793,0.004800355],"study_design_scores_gemma":[0.0003098476,0.00004136194,0.02143774,0.000006166837,0.000007439354,0.0000015383,0.00007441881,0.00007087059,0.9764431,0.0000196666,0.001510368,0.00007746089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966327,0.0001546409,0.0005022677,0.00003115601,0.00002033437,0.0001056338,0.000003977712,0.00000546531,0.002543834],"genre_scores_gemma":[0.9977596,0.0003472729,0.0001313909,0.00003299145,0.00003453676,0.00001195007,0.0004671178,0.000009450489,0.001205684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0192538,"threshold_uncertainty_score":0.647974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007231752595758159,"score_gpt":0.2257172304065639,"score_spread":0.2184854778108057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}