{"id":"W2993552927","doi":"10.1186/s41199-019-0045-0","title":"Genomic and human papillomavirus profiling of an oral cancer cohort identifies TP53 as a predictor of overall survival","year":2019,"lang":"en","type":"article","venue":"Cancers of the Head & Neck","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research; London Health Sciences Centre; Western University","funders":"Canadian Institutes of Health Research","keywords":"Human papillomavirus; Oncology; Cohort; Profiling (computer programming); Survival analysis; Internal medicine; Overall survival; Medicine; Biology; Computational biology; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003430554,0.0001377058,0.0002288442,0.0008017481,0.000346686,0.0005037558,0.0001581399,0.0002198058,0.001980079],"category_scores_gemma":[0.001161787,0.0001181014,0.0001975883,0.0006132196,0.0002265125,0.0001864477,0.0003479716,0.0002264687,0.0002597009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001870991,"about_ca_system_score_gemma":0.0001844995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002005961,"about_ca_topic_score_gemma":0.002634087,"domain_scores_codex":[0.9998023,0.00003040518,0.00001578064,0.00005948875,0.00004079822,0.00005136665],"domain_scores_gemma":[0.9995794,0.00009973186,0.0001111082,0.00006154729,0.00006069031,0.00008770246],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002532766,0.00003282483,0.9928988,0.000005172857,0.00004105346,0.0001132427,0.00004737927,0.00005295378,0.00362146,0.00001160174,0.0001381293,0.002784102],"study_design_scores_gemma":[0.000005802947,0.0001226262,0.9982969,0.000002174311,0.00003693758,0.0004772867,0.0001230805,0.0002015646,0.0005132368,0.00002640444,0.000191853,0.000002190911],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995975,0.00004655045,0.00005295684,0.00001012872,0.000001888035,0.000002719124,0.0001933301,0.000002722756,0.00009226223],"genre_scores_gemma":[0.9995615,0.00002761174,0.00004406187,0.000007585947,0.000003432856,0.000003571747,0.0002571137,0.000001544731,0.00009350618],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002005961,"threshold_uncertainty_score":0.006623983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02664606422836267,"score_gpt":0.3254853303816789,"score_spread":0.2988392661533162,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}