{"id":"W2993587902","doi":"","title":"Alterations in mTOR Signaling in the Genetic BTBR Mouse Model of Autism Spectrum Disorder","year":2012,"lang":"en","type":"article","venue":"Journal of undergraduate research in Alberta","topic":"Tuberous Sclerosis Complex Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"","keywords":"PI3K/AKT/mTOR pathway; Tuberous sclerosis; Autism spectrum disorder; Autism; Neurodevelopmental disorder; Signal transduction; Epilepsy; Neuroscience; Population; Medicine; Endocrinology; Internal medicine; Biology; Genetics; Pathology; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004829731,0.001446964,0.0008632665,0.002769586,0.0008230841,0.0007526234,0.000855409,0.002121083,0.007319964],"category_scores_gemma":[0.0002778116,0.0006659165,0.001004806,0.0006689372,0.001026353,0.0006684038,0.0004519504,0.002709593,0.002503882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00099899,"about_ca_system_score_gemma":0.0004941754,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002099185,"about_ca_topic_score_gemma":0.002878511,"domain_scores_codex":[0.9992268,0.00007605732,0.0001099772,0.0002149759,0.0002385271,0.0001337718],"domain_scores_gemma":[0.9993844,0.00005679199,0.0002416164,0.00004145025,0.0000544008,0.0002213348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006613717,0.0003124526,0.0002102615,0.0001040043,0.00001441054,0.0003361477,0.00004778023,0.0001158921,0.9966124,0.0003160643,0.000278134,0.0009911739],"study_design_scores_gemma":[0.0008565169,0.005902166,0.01870204,0.0002554606,0.0002401524,0.005265695,0.0004565995,0.004244559,0.9457734,0.000718325,0.01749519,0.00008990202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9695324,0.004085991,0.007501094,0.001536926,0.0004102401,0.0003826988,0.009561829,0.001362342,0.005626483],"genre_scores_gemma":[0.9431999,0.004461013,0.01598836,0.000745908,0.0001367133,0.001137085,0.007160856,0.0005559842,0.02661414],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007319964,"threshold_uncertainty_score":0.02448767,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1236515032480948,"score_gpt":0.3807674637595696,"score_spread":0.2571159605114748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}