{"id":"W2993693045","doi":"10.2967/jnumed.119.231068","title":"Differential Expression of Glucose Transporters and Hexokinases in Prostate Cancer with a Neuroendocrine Gene Signature: A Mechanistic Perspective for <sup>18</sup>F-FDG Imaging of PSMA-Suppressed Tumors","year":2019,"lang":"en","type":"article","venue":"Journal of Nuclear Medicine","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Windsor","funders":"Canadian Institutes of Health Research","keywords":"Neuroendocrine tumors; Prostate cancer; Cancer research; Glucose transporter; Gene signature; Biology; Glucokinase; Gene expression; Gene; Cancer; Endocrinology; Biochemistry; Genetics; Insulin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003819976,0.0002509661,0.0003230984,0.0006582506,0.0001188767,0.0007137185,0.0002831811,0.0002253089,0.0004623547],"category_scores_gemma":[0.0003851839,0.00009846078,0.0003434635,0.001015035,0.0002721328,0.0003507489,0.0001850483,0.0003235929,0.00007707258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003944425,"about_ca_system_score_gemma":0.0003494872,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001105365,"about_ca_topic_score_gemma":0.00182202,"domain_scores_codex":[0.9998939,0.00002038343,0.00001401697,0.00003316733,0.00002240087,0.0000160108],"domain_scores_gemma":[0.9997836,0.00005916943,0.00009372384,0.00002052879,0.00002506663,0.00001799882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001237588,0.0002314536,0.4300802,0.0007018562,0.0004448906,0.001011053,0.000323977,0.004524807,0.4681758,0.00204485,0.0009564051,0.09026721],"study_design_scores_gemma":[0.00005669756,0.0006333161,0.7954417,0.0001227678,0.0003937169,0.00402902,0.0009878334,0.02862984,0.153728,0.006404491,0.009509327,0.00006330127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9789237,0.004238547,0.01336533,0.0007979496,0.00001792042,0.00005176725,0.001547228,0.0001052209,0.0009523039],"genre_scores_gemma":[0.9864391,0.002042974,0.01012352,0.0001342063,0.00001451228,0.00002868952,0.001009949,0.000007863065,0.0001993614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001105365,"threshold_uncertainty_score":0.002861917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01246741005659849,"score_gpt":0.286186905227933,"score_spread":0.2737194951713345,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}