{"id":"W2993693045","doi":"10.2967/jnumed.119.231068","title":"Differential Expression of Glucose Transporters and Hexokinases in Prostate Cancer with a Neuroendocrine Gene Signature: A Mechanistic Perspective for <sup>18</sup>F-FDG Imaging of PSMA-Suppressed Tumors","year":2019,"lang":"en","type":"article","venue":"Journal of Nuclear Medicine","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of Windsor","funders":"Canadian Institutes of Health Research","keywords":"Neuroendocrine tumors; Prostate cancer; Cancer research; Glucose transporter; Gene signature; Biology; Glucokinase; Gene expression; Gene; Cancer; Endocrinology; Biochemistry; Genetics; Insulin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000135416,0.0002007332,0.0008021254,0.0003782627,0.00002861173,0.000005384077,0.0001013428,0.00002528279,0.000258974],"category_scores_gemma":[0.00006946993,0.0001183528,0.00009143921,0.0002070475,0.0002105095,0.0001199951,0.00002178479,0.0003196531,1.432992e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001123604,"about_ca_system_score_gemma":0.0001603417,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001254175,"about_ca_topic_score_gemma":0.000004468541,"domain_scores_codex":[0.9983946,0.00004829392,0.0005270216,0.0002288214,0.0005304831,0.0002707971],"domain_scores_gemma":[0.9987513,0.000113083,0.0003952043,0.0001490403,0.0004209823,0.0001704133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02791442,0.0004839555,0.01720372,0.001182845,0.000211616,0.00103196,0.004800602,0.0001296561,0.9454009,0.00004788579,0.0003399192,0.001252512],"study_design_scores_gemma":[0.1164675,0.02728958,0.1289466,0.0206053,0.002039452,0.002196577,0.02990419,0.009018803,0.6618547,0.0005779009,0.0005100568,0.0005892814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931174,0.002933379,0.00004929855,0.002810121,0.00006982725,0.0009276389,0.00004426259,0.000006583249,0.0000414682],"genre_scores_gemma":[0.9980865,0.001256768,0.0003254002,0.00009635086,0.0001119481,0.00001166402,0.000008682283,0.00004427956,0.00005842905],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2835462,"threshold_uncertainty_score":0.4826286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01246741005659849,"score_gpt":0.286186905227933,"score_spread":0.2737194951713345,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}