{"id":"W2994178787","doi":"10.1182/blood.v108.11.847.847","title":"Aurora Kinases as Therapeutic Targets in Multiple Myeloma.","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Aurora inhibitor; Aurora A kinase; Aurora kinase; Cancer research; Bone marrow; Aurora B kinase; Multiple myeloma; Biology; Kinase; Plasma cell; Centrosome; Mitosis; Gene knockdown; Plasma Cell Myeloma; Cytokinesis; Cell cycle; Cell biology; Cell culture; Cell; Immunology; Cell division; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002151944,0.0004772526,0.0003918449,0.0004575448,0.0002124573,0.0004997512,0.0002793302,0.0004286444,0.00199577],"category_scores_gemma":[0.00008409702,0.0001398013,0.0003003202,0.0004977847,0.0001794937,0.00023129,0.0002622746,0.0008114344,0.0006930167],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006536368,"about_ca_system_score_gemma":0.0002614502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004292786,"about_ca_topic_score_gemma":0.001214062,"domain_scores_codex":[0.9998989,0.00001204319,0.000009659419,0.00002248017,0.00003475387,0.00002211278],"domain_scores_gemma":[0.9999442,0.000008790469,0.00001753926,0.000005510302,0.0000100164,0.00001394565],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00104694,0.0002577702,0.001531799,0.0009150578,0.00009196455,0.0003219667,0.00003622634,0.0007517379,0.9299335,0.0005515779,0.001467997,0.06309342],"study_design_scores_gemma":[0.000462918,0.003608479,0.01780176,0.0001429108,0.0002834212,0.003743481,0.00006471728,0.001459411,0.8855698,0.0006622557,0.08617842,0.00002251101],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.6801801,0.2927403,0.006408441,0.002129469,0.0004100574,0.0003255861,0.002181288,0.0007998493,0.0148249],"genre_scores_gemma":[0.9377343,0.05057947,0.003946737,0.0003639643,0.00009769192,0.0001076245,0.001855468,0.00004393777,0.005270848],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.00199577,"threshold_uncertainty_score":0.006676495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006634941425975072,"score_gpt":0.2174251598838858,"score_spread":0.2107902184579107,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}