{"id":"W2994312780","doi":"10.1177/1078155219890659","title":"Toxic epidermal necrolysis associated with pembrolizumab","year":2019,"lang":"en","type":"article","venue":"Journal of Oncology Pharmacy Practice","topic":"Drug-Induced Adverse Reactions","field":"Medicine","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cégep de l'Outaouais; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Toxic epidermal necrolysis; Pembrolizumab; Medicine; Rash; Erythroderma; Dermatology; Maculopapular rash; Skin biopsy; Paraneoplastic pemphigus; Pathology; Biopsy; Cancer; Internal medicine; Immunology; Immunotherapy; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001435674,0.0002000313,0.0007320073,0.0003331051,0.00008622035,0.00002311988,0.0001586427,0.000125262,0.0003414782],"category_scores_gemma":[0.002750947,0.0001534891,0.0002298597,0.0004622851,0.00007176923,0.001432164,0.00003890616,0.001572657,0.0003041992],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009658224,"about_ca_system_score_gemma":0.001856707,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002616329,"about_ca_topic_score_gemma":0.000005206904,"domain_scores_codex":[0.9976807,0.0004901062,0.0006812057,0.0002010446,0.0005794645,0.0003674758],"domain_scores_gemma":[0.9943001,0.002325142,0.001782042,0.0002320242,0.001014252,0.0003464884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.02435453,0.02214174,0.08194449,0.0002264956,0.02485369,0.03410897,0.003212679,0.002355402,0.4441037,0.0004821571,0.0192709,0.3429452],"study_design_scores_gemma":[0.0288978,0.00144085,0.02508043,0.0001498955,0.004844159,0.04293002,0.001370574,0.000454276,0.004575673,0.00001372453,0.8900011,0.0002414936],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.823213,0.0001829378,0.00006977145,0.02283525,0.0009331552,0.0003183692,0.000002575868,0.00003614768,0.1524088],"genre_scores_gemma":[0.9907635,0.0002721887,0.00179773,0.004552645,0.0004223997,0.000004423865,0.000004672393,0.00003970205,0.002142686],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8707302,"threshold_uncertainty_score":0.68325,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03781405407038124,"score_gpt":0.3894478436511624,"score_spread":0.3516337895807811,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}