{"id":"W2994525931","doi":"10.1101/19013524","title":"HIV-1 founder variant multiplicity is determined by the infection stage of the source partner","year":2019,"lang":"en","type":"preprint","venue":"medRxiv","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Global Health Research","funders":"","keywords":"Founder effect; Bottleneck; Human immunodeficiency virus (HIV); Transmission (telecommunications); Biology; Genetic diversity; Multiplicity of infection; Genetics; Evolutionary biology; Immunology; Medicine; Genotype; Population; Gene; Computer science; Environmental health; Telecommunications; Haplotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008499139,0.0002084627,0.0004065196,0.0003754722,0.0002359207,0.001071799,0.0003270981,0.0004254322,0.004622564],"category_scores_gemma":[0.006255779,0.0002106132,0.0003929926,0.0002680304,0.0002992524,0.0005296872,0.0004853531,0.0006960392,0.0005771107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003329678,"about_ca_system_score_gemma":0.0002076577,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001085677,"about_ca_topic_score_gemma":0.0007652358,"domain_scores_codex":[0.999486,0.0002200798,0.00001715863,0.0001566718,0.00005052276,0.00006957116],"domain_scores_gemma":[0.9957584,0.002648768,0.0007468286,0.0003935998,0.0001386633,0.0003137306],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002150528,0.0003147935,0.8789159,0.00009454368,0.0004121399,0.0004239514,0.0002481566,0.03307072,0.05321701,0.003673862,0.001460505,0.02601799],"study_design_scores_gemma":[0.0000698781,0.0005775251,0.7225804,0.00003673272,0.0002678338,0.001455799,0.000465144,0.2499202,0.01236499,0.01097542,0.001222317,0.00006377314],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922161,0.0001933906,0.006075515,0.0001291958,0.0000123601,0.000008735101,0.0004031637,0.00003472777,0.0009268376],"genre_scores_gemma":[0.9989539,0.0000473702,0.0005908476,0.0000151322,0.000005005655,0.000003422952,0.000124034,0.00001242724,0.0002478161],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004622564,"threshold_uncertainty_score":0.01546407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02583760257755899,"score_gpt":0.2804114361346383,"score_spread":0.2545738335570793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}