{"id":"W2994647402","doi":"10.1128/mbio.02985-19","title":"RIP1, RIP3, and MLKL Contribute to Cell Death Caused by Clostridium perfringens Enterotoxin","year":2019,"lang":"en","type":"article","venue":"mBio","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Necroptosis; Clostridium perfringens; Enterotoxin; Programmed cell death; Microbiology; Apoptosis; Kinase; Necrosis; Virulence; Biology; Chemistry; Cell biology; Biochemistry; Escherichia coli; Bacteria; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002287495,0.0005743106,0.0002668519,0.0002789363,0.0002073713,0.0003773865,0.0001944023,0.000505719,0.001808519],"category_scores_gemma":[0.0001823082,0.0001509107,0.0004131387,0.000124236,0.0002371979,0.0004222184,0.0002812192,0.0008220279,0.0004803437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003686705,"about_ca_system_score_gemma":0.0002215826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002338215,"about_ca_topic_score_gemma":0.0003253468,"domain_scores_codex":[0.999817,0.0000318796,0.00001594863,0.00002779326,0.00003443563,0.00007303495],"domain_scores_gemma":[0.9998479,0.00001585106,0.00005863955,0.000009237794,0.00001876255,0.00004969446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007037965,0.000107213,0.001025311,0.0002001547,0.00001560061,0.0003017195,0.00002284904,0.00007367916,0.9941203,0.00009412732,0.0001641592,0.003170954],"study_design_scores_gemma":[0.0001758979,0.001268375,0.06638617,0.00004468772,0.0001224022,0.003401665,0.0001752752,0.002049488,0.9196835,0.0003643323,0.006307114,0.00002114554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9792011,0.0143083,0.00270636,0.000417292,0.00005722647,0.00007300492,0.0003186602,0.0001095622,0.002808511],"genre_scores_gemma":[0.9924987,0.003552737,0.001511038,0.0001623549,0.00002808378,0.00003753594,0.000370471,0.00001262359,0.001826473],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001808519,"threshold_uncertainty_score":0.00605011,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01466217219561385,"score_gpt":0.2701979060806374,"score_spread":0.2555357338850235,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}