{"id":"W2994726901","doi":"10.1016/j.cjca.2019.11.035","title":"Acute Coronary Syndrome With Immune Checkpoint Inhibitors: A Proof-of-Concept Case and Pharmacovigilance Analysis of a Life-Threatening Adverse Event","year":2019,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Pharmacovigilance and Adverse Drug Reactions","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":50,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Roche; Novartis; Merck Sharp and Dohme; Bristol-Myers Squibb","keywords":"Medicine; Pharmacovigilance; Adverse effect; Acute coronary syndrome; Event (particle physics); Intensive care medicine; Internal medicine; Myocardial infarction","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002813754,0.0009133488,0.0009179902,0.0009000083,0.001322186,0.003424485,0.001134376,0.004617795,0.00354828],"category_scores_gemma":[0.01291304,0.0004973443,0.001873921,0.0003228551,0.001180515,0.001351737,0.001405939,0.003494474,0.0008832066],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001869418,"about_ca_system_score_gemma":0.002349765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009817829,"about_ca_topic_score_gemma":0.001213843,"domain_scores_codex":[0.9967375,0.00098366,0.0004215678,0.0004732356,0.0009852241,0.0003987434],"domain_scores_gemma":[0.9909038,0.004940491,0.001702677,0.0004726852,0.0008142533,0.001166106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.003703526,0.002830083,0.1537632,0.00133201,0.0005028085,0.7323855,0.002379744,0.00133648,0.01344439,0.009629388,0.01426238,0.06443062],"study_design_scores_gemma":[0.001240823,0.006729613,0.03811307,0.001018407,0.0008822231,0.8891304,0.00168727,0.006039758,0.01056779,0.005597373,0.03884462,0.0001486548],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.880286,0.01430182,0.02676456,0.03950001,0.0009797683,0.003359224,0.001675326,0.0003424554,0.03279075],"genre_scores_gemma":[0.9749315,0.003237811,0.009217678,0.008882363,0.001261612,0.0002391361,0.0005866818,0.00005036928,0.001592765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004617795,"threshold_uncertainty_score":0.01488072,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03395011915084729,"score_gpt":0.3392945134256134,"score_spread":0.3053443942747661,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}