{"id":"W2994898104","doi":"10.1080/09553002.2019.1704913","title":"A case example of a radiation-relevant adverse outcome pathway to lung cancer","year":2019,"lang":"en","type":"article","venue":"International Journal of Radiation Biology","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada","funders":"","keywords":"Adverse Outcome Pathway; DNA damage; DNA repair; Computational biology; Ionizing radiation; Computer science; Biology; Bioinformatics; DNA; Genetics; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002898301,0.00009979486,0.0001912183,0.0001848092,0.00001880615,0.000008551934,0.000207264,0.00009753656,0.0001912835],"category_scores_gemma":[0.00009647492,0.00008916369,0.0001522666,0.00006880621,0.00002115074,0.000009715543,0.00006037239,0.00007671084,0.000006729742],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009490444,"about_ca_system_score_gemma":0.0001826935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002531775,"about_ca_topic_score_gemma":0.00008001069,"domain_scores_codex":[0.9989743,0.00006601424,0.0005113847,0.0001628957,0.0001625439,0.0001228109],"domain_scores_gemma":[0.9989232,0.00003910185,0.0004589327,0.0001355762,0.0003633304,0.00007987208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002933228,0.00009948334,0.3392377,0.00001325947,0.0004367783,0.00007300116,0.0002427878,0.003863479,0.6237715,0.0008633457,0.0007976374,0.03030767],"study_design_scores_gemma":[0.006890874,0.002136222,0.1674541,0.00006676733,0.0001261285,0.003128269,0.0003720513,0.001590206,0.5447415,0.0001596189,0.2726847,0.0006495016],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932522,0.0005386479,0.003811473,0.0005301706,0.001388941,0.000169016,0.0001943551,0.000002127973,0.0001130351],"genre_scores_gemma":[0.9980909,0.0001974844,0.0004512293,0.0005435012,0.0004548855,0.000008002452,0.00006363444,0.000009595419,0.0001808165],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2718871,"threshold_uncertainty_score":0.3635989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01546474333121015,"score_gpt":0.3227613702477661,"score_spread":0.3072966269165559,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}