{"id":"W2994946603","doi":"10.1002/rth2.12287","title":"Direct oral anticoagulants in antiphospholipid syndrome with venous thromboembolism: Impact of the European Medicines Agency guidance","year":2019,"lang":"en","type":"article","venue":"Research and Practice in Thrombosis and Haemostasis","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Antiphospholipid syndrome; Medicine; Thrombosis; Autoantibody; Venous thrombosis; In vivo; Oxidative stress; Thrombus; Internal medicine; Gastroenterology; Immunology; Antibody; Biology; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008987862,0.000758288,0.002073872,0.002076427,0.0005439685,0.002843388,0.002031765,0.01013246,0.004584776],"category_scores_gemma":[0.01586112,0.0003524642,0.00229438,0.001747494,0.0009289692,0.001847234,0.001161357,0.00627072,0.002226621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002210725,"about_ca_system_score_gemma":0.006887163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006472348,"about_ca_topic_score_gemma":0.009991364,"domain_scores_codex":[0.9942762,0.001630779,0.0012959,0.0002630423,0.002248435,0.0002856561],"domain_scores_gemma":[0.985094,0.006558405,0.002578161,0.0003353595,0.004328264,0.001105827],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0005446872,0.0002726385,0.001325888,0.002913317,0.0002169893,0.0004621263,0.00007927022,0.0004953024,0.0005006182,0.008124512,0.4768567,0.5082079],"study_design_scores_gemma":[0.00037695,0.0002003367,0.003679503,0.006814561,0.0002854675,0.0007747188,0.00004178806,0.0003692196,0.0003456341,0.002593401,0.9844826,0.0000359362],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.00198865,0.7014893,0.001556403,0.2397586,0.01107094,0.0001543495,0.001225094,0.0001950436,0.04256165],"genre_scores_gemma":[0.04079609,0.6890931,0.01379051,0.2088359,0.01874942,0.0007760107,0.002964798,0.0001530672,0.02484118],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01013246,"threshold_uncertainty_score":0.04753292,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07527337516104819,"score_gpt":0.3804801061782759,"score_spread":0.3052067310172277,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}