{"id":"W2994967047","doi":"10.1111/apt.15581","title":"Review article: clinical pharmacology of current and investigational hepatitis B virus therapies","year":2019,"lang":"en","type":"review","venue":"Alimentary Pharmacology & Therapeutics","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Liver Centre; University of Toronto; University Health Network","funders":"","keywords":"Medicine; HBsAg; Hepatitis B virus; Hepatitis B; Pharmacokinetics; Drug; Internal medicine; Clinical trial; Pharmacology; Virus; Virology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008713681,0.000946016,0.001816338,0.002652933,0.0003450156,0.00209906,0.001025768,0.001922215,0.01292547],"category_scores_gemma":[0.002150356,0.0002652376,0.0009046812,0.002563807,0.0004363169,0.00151811,0.0008376917,0.002257372,0.004476564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001013711,"about_ca_system_score_gemma":0.0022978,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008444275,"about_ca_topic_score_gemma":0.001221515,"domain_scores_codex":[0.9993432,0.0001654873,0.0001345836,0.0000761944,0.0002271619,0.00005325439],"domain_scores_gemma":[0.9986338,0.0005859248,0.0002414828,0.00003393645,0.0003805809,0.0001243059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002088997,0.0001033365,0.0002030089,0.04135734,0.0001605295,0.0002885579,0.00007717262,0.000247048,0.0009785178,0.002197253,0.1599221,0.7942563],"study_design_scores_gemma":[0.00005922718,0.0001516884,0.0007984106,0.012553,0.0002218604,0.001560294,0.00006308663,0.0000801284,0.0002917878,0.001106843,0.9830918,0.00002198579],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001534817,0.9927934,0.0001499312,0.001262111,0.002526044,0.00002561515,0.00007333836,0.00001654288,0.002999576],"genre_scores_gemma":[0.00117017,0.9921821,0.0002779214,0.001323989,0.003106673,0.00002804872,0.0001226862,0.000004871786,0.001783515],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01292547,"threshold_uncertainty_score":0.04324001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2464467679843872,"score_gpt":0.4991786279890949,"score_spread":0.2527318600047077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}