{"id":"W2995043367","doi":"10.3390/ijms21186453","title":"Elucidating the Role of Ezh2 in Tolerogenic Function of NOD Bone Marrow-Derived Dendritic Cells Expressing Constitutively Active Stat5b","year":2020,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; IRF4; Dendritic cell; CD11c; NOD mice; Cell biology; IRF8; Immune tolerance; Nod; Cancer research; Immunology; Transcription factor; Immune system; Autoimmunity; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001215149,0.0001756467,0.0001511475,0.0001138533,0.0001032209,0.0001918293,0.0001169342,0.0001851514,0.0006135564],"category_scores_gemma":[0.00004837732,0.00009509055,0.0001454846,0.00007894614,0.0001784215,0.0001932896,0.0001455831,0.0003225078,0.0001550218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000193641,"about_ca_system_score_gemma":0.0001160594,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002621093,"about_ca_topic_score_gemma":0.0005544432,"domain_scores_codex":[0.9999232,0.00001091736,0.000006342385,0.00001679696,0.00001838832,0.00002438211],"domain_scores_gemma":[0.9999692,0.000004840219,0.000009769068,0.000002869316,0.000002909286,0.00001038479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001056379,0.00000826357,0.0005347037,0.0000268983,0.000002815168,0.00003816971,0.000008693867,0.00005297864,0.9984567,0.00008758534,0.000009653622,0.0006677861],"study_design_scores_gemma":[0.00003505606,0.0002049778,0.01679208,0.000007458153,0.00002254133,0.0003092461,0.00007651188,0.001803451,0.978561,0.0001147695,0.002068522,0.000004350397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996645,0.001243272,0.001361371,0.0000802367,0.00000698543,0.000007011212,0.0001448027,0.00001277366,0.0004985737],"genre_scores_gemma":[0.9975332,0.0006318295,0.0008649382,0.00004886222,0.000005890804,0.000009230816,0.0002223231,0.000005046289,0.0006786087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006135564,"threshold_uncertainty_score":0.002052605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01370209066698071,"score_gpt":0.2509141488114194,"score_spread":0.2372120581444387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}