{"id":"W2995076193","doi":"10.3747/co.26.5177","title":"Impact of the Gut Microbiome on Immune Checkpoint Inhibitor Efficacy—A Systematic Review","year":2019,"lang":"en","type":"review","venue":"Current Oncology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Gut microbiome; Medicine; Microbiome; Immune system; Immune checkpoint; Computational biology; Bioinformatics; Immunology; Gut flora; Biology; Immunotherapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005114852,0.001352602,0.007038435,0.00868319,0.0005434849,0.002563804,0.001255075,0.001587673,0.004320188],"category_scores_gemma":[0.02432372,0.000835722,0.00759953,0.009611381,0.0006562465,0.002014766,0.001233684,0.0008662818,0.0003537443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002066899,"about_ca_system_score_gemma":0.006930675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005223883,"about_ca_topic_score_gemma":0.01284285,"domain_scores_codex":[0.9953085,0.001377616,0.001876297,0.0004525518,0.0008019037,0.0001830495],"domain_scores_gemma":[0.9776952,0.01548938,0.004614401,0.000257423,0.00170565,0.0002380942],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.000321983,0.00001672073,0.001968969,0.9574373,0.01382264,0.0001095465,0.0001208889,0.00007957783,0.0001912732,0.0001247841,0.0009554231,0.02485086],"study_design_scores_gemma":[0.0003363656,0.0002861943,0.01151103,0.829467,0.1428464,0.0005374727,0.000250151,0.0001185975,0.0002559125,0.0002711999,0.01407164,0.00004808925],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001901862,0.9969285,0.00008848119,0.0002008382,0.00007069219,0.0001253664,0.0004657829,0.000005087741,0.0002133008],"genre_scores_gemma":[0.02556856,0.9726086,0.0004435739,0.0004689669,0.0001009832,0.0003351693,0.0003621696,0.000005659359,0.0001062493],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00868319,"threshold_uncertainty_score":0.02705026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1014873706829623,"score_gpt":0.4534471642647652,"score_spread":0.351959793581803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}