{"id":"W2995076193","doi":"10.3747/co.26.5177","title":"Impact of the Gut Microbiome on Immune Checkpoint Inhibitor Efficacy—A Systematic Review","year":2019,"lang":"en","type":"review","venue":"Current Oncology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Gut microbiome; Medicine; Microbiome; Immune system; Immune checkpoint; Computational biology; Bioinformatics; Immunology; Gut flora; Biology; Immunotherapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006848915,0.0005971793,0.00363751,0.0001096254,0.00006264378,0.000009842868,0.0008875357,0.0006238258,0.00004544995],"category_scores_gemma":[0.0003136737,0.0003302179,0.002536073,0.0002732349,0.0001405984,0.000001582358,0.0004034803,0.0006058206,0.000256237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003910442,"about_ca_system_score_gemma":0.001678939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005669993,"about_ca_topic_score_gemma":0.000002410125,"domain_scores_codex":[0.9961995,0.0009412929,0.001671691,0.0006005053,0.0001332644,0.0004537518],"domain_scores_gemma":[0.9962727,0.00009433067,0.001840759,0.001548592,0.0001460863,0.00009747457],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001441831,0.0005124502,0.000002765118,0.9602811,0.0003941414,8.826153e-7,0.00001255455,1.997209e-7,0.004515485,0.000006881569,0.007098754,0.02716032],"study_design_scores_gemma":[0.0003350787,0.0007376822,0.00002717755,0.3773687,0.001494424,0.00009604942,0.000001357822,8.793171e-8,0.00006283318,4.325276e-7,0.6196165,0.0002596575],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004119959,0.9924445,0.000001727077,0.00004033151,0.00195784,0.004764303,0.0002295778,0.000008253253,0.0001415403],"genre_scores_gemma":[0.0001212931,0.9984031,0.000007642529,0.00006814257,0.0002792304,0.0001426195,0.0005854415,0.0000625376,0.000330036],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6125177,"threshold_uncertainty_score":0.999915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1014873706829623,"score_gpt":0.4534471642647652,"score_spread":0.351959793581803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}