{"id":"W2995099757","doi":"10.1016/j.jval.2019.09.2178","title":"PNS278 A REVIEW OF HEALTH TECHNOLOGY ASSESSMENT GUIDELINES ON THE APPROVAL OF BIOSIMILARS","year":2019,"lang":"en","type":"review","venue":"Value in Health","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biosimilar; Medicine; Drug approval; Health technology; Pharmacology; Political science; Health care; Drug; Internal medicine; Law","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003908839,0.001099317,0.001871404,0.005377511,0.0004451944,0.002027914,0.001442491,0.002783338,0.008435482],"category_scores_gemma":[0.007754925,0.0004417697,0.001729447,0.004687272,0.0007390727,0.001642518,0.00125634,0.002941572,0.002896493],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002488655,"about_ca_system_score_gemma":0.007355697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003620529,"about_ca_topic_score_gemma":0.005515001,"domain_scores_codex":[0.9980562,0.0004996161,0.0004145152,0.0001794342,0.000730489,0.000119737],"domain_scores_gemma":[0.9948896,0.002926448,0.0008034559,0.00009000394,0.001137207,0.0001533052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001668725,0.00006195206,0.0001184783,0.05273847,0.0002339509,0.0001820968,0.00006773834,0.0002612204,0.001001696,0.007355912,0.0924095,0.8454021],"study_design_scores_gemma":[0.00004564349,0.00006776524,0.0004997412,0.02720919,0.0003570641,0.0003945591,0.0000328695,0.00005751062,0.0003542152,0.001684328,0.9692798,0.00001737425],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008502555,0.993913,0.0002949321,0.001876298,0.000751265,0.00003358298,0.0001550769,0.00001214731,0.002878738],"genre_scores_gemma":[0.0007253117,0.9946533,0.0006215136,0.00225798,0.0003159597,0.00004185635,0.0001630924,0.000004554872,0.001216301],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.008435482,"threshold_uncertainty_score":0.02821952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3409310907795893,"score_gpt":0.4982831851940395,"score_spread":0.1573520944144501,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}