{"id":"W2995119490","doi":"10.1038/s41598-019-55426-x","title":"Bronchial epithelium repair by Esculentin-1a-derived antimicrobial peptides: involvement of metalloproteinase-9 and interleukin-8, and evaluation of peptides’ immunogenicity","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; National Heart, Lung, and Blood Institute; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Sapienza Università di Roma","keywords":"Cystic fibrosis; Wound healing; Immunogenicity; Pseudomonas aeruginosa; Antimicrobial peptides; Epithelium; Immune system; Cystic fibrosis transmembrane conductance regulator; Biology; Immunology; Peptide; Cancer research; Medicine; Pathology; Biochemistry; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002847367,0.0003177892,0.0002175453,0.0001605051,0.00008143332,0.000196934,0.00007219236,0.000295093,0.0006152185],"category_scores_gemma":[0.0001512329,0.00008053733,0.0001775429,0.0000935953,0.0001999839,0.0002455616,0.000117865,0.0003518939,0.00009841516],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008096045,"about_ca_system_score_gemma":0.00005902746,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005528901,"about_ca_topic_score_gemma":0.00005767909,"domain_scores_codex":[0.9998751,0.00005257115,0.00001080347,0.0000128914,0.0000227442,0.00002584832],"domain_scores_gemma":[0.9998864,0.00003373375,0.00002880526,0.00001068713,0.00001457412,0.00002576511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001461651,0.00003091294,0.0001046698,0.00002771789,0.00000173144,0.00002639729,0.000005817637,0.00002529398,0.9990779,0.00001356928,0.000003215897,0.0005365729],"study_design_scores_gemma":[0.00001978462,0.001239171,0.003041117,0.000005881708,0.00001395136,0.0001560744,0.00002399914,0.0005504369,0.9945416,0.00003580257,0.0003697553,0.000002396199],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970113,0.001694452,0.0009173381,0.00002742348,0.00001443862,0.00002056842,0.00004245743,0.000006866392,0.0002652795],"genre_scores_gemma":[0.9971137,0.0007247904,0.001623604,0.00002647354,0.00001522736,0.0000220503,0.0000779196,0.000003319676,0.0003927975],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006152185,"threshold_uncertainty_score":0.002058089,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01188059501543495,"score_gpt":0.2303660760759746,"score_spread":0.2184854810605397,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}