{"id":"W2995147881","doi":"10.1007/s10787-019-00678-2","title":"Unexpected mechanism of colitis amelioration by artesunate, a natural product from Artemisia annua L.","year":2019,"lang":"en","type":"article","venue":"Inflammopharmacology","topic":"Natural Compounds in Disease Treatment","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Natural Science Foundation of China","keywords":"Artesunate; Pharmacology; Acquired immune system; Immunology; Triptolide; Innate immune system; Apoptosis; Artemisia annua; In vivo; Artemisinin; Biology; Medicine; Immune system; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000912003,0.0002487121,0.0005340806,0.0001871934,0.00003896369,0.00001066102,0.0001528223,0.0001316417,0.001355979],"category_scores_gemma":[0.00004578229,0.0002294453,0.0001258836,0.0003664664,0.00008627234,0.0001381315,0.00006634434,0.0003341699,0.0002137594],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002284669,"about_ca_system_score_gemma":0.0001421448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001027622,"about_ca_topic_score_gemma":0.00001037031,"domain_scores_codex":[0.9982458,0.000132971,0.0004636249,0.0004934445,0.0003292188,0.0003348871],"domain_scores_gemma":[0.9987838,0.0001268731,0.0002369254,0.0003804124,0.0003166241,0.0001553446],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001631395,0.0002979234,0.00292648,0.00005074276,0.000422649,0.0001172023,0.0001466866,0.000004590232,0.978688,0.0004479348,0.01248735,0.002779031],"study_design_scores_gemma":[0.009383319,0.0008197338,0.05998359,0.00007753752,0.0005495707,0.00006263419,0.0000844252,0.00075339,0.9208199,0.002021615,0.005072066,0.0003721894],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934238,0.001735815,0.000005676233,0.001207188,0.001283804,0.001064173,0.0001397339,0.0001464046,0.000993435],"genre_scores_gemma":[0.9965176,0.00004329306,0.0004597084,0.0005458033,0.0002309715,0.0000853985,0.0005134997,0.00003184802,0.001571874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05786808,"threshold_uncertainty_score":0.9995569,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00540328419614228,"score_gpt":0.2673223102950075,"score_spread":0.2619190260988652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}