{"id":"W2995177489","doi":"10.1084/jem.20191030","title":"c-Maf regulates the plasticity of group 3 innate lymphoid cells by restraining the type 1 program","year":2019,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Human Genome Research Institute; National Institutes of Health","keywords":"Innate lymphoid cell; Chromatin; Effector; Biology; Transcription factor; C-C chemokine receptor type 6; RAR-related orphan receptor gamma; Regulator; Cell biology; Immunology; Immunity; Inflammation; Genetics; Immune system; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001103101,0.0003281094,0.0001484861,0.0002489148,0.0002192605,0.0003624492,0.0001605273,0.0002294787,0.0008364951],"category_scores_gemma":[0.00009753851,0.00008270763,0.000167698,0.0001339983,0.0003540932,0.0001730392,0.0002207196,0.000445663,0.0002142978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003614103,"about_ca_system_score_gemma":0.0002750999,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009442492,"about_ca_topic_score_gemma":0.001632541,"domain_scores_codex":[0.9998645,0.00002052519,0.000006756854,0.00002903958,0.00003213153,0.00004703162],"domain_scores_gemma":[0.999894,0.0000116271,0.00003003486,0.00001537111,0.0000128272,0.00003608221],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004057992,0.000005400248,0.0002600015,0.000006699215,9.403502e-7,0.00002393766,0.000007712023,0.00002338196,0.9989333,0.0001061867,0.00001124579,0.0005805318],"study_design_scores_gemma":[0.00001023893,0.0001030057,0.01818079,0.000006581936,0.000007769274,0.0002042063,0.00005190328,0.001245133,0.9781899,0.0001221892,0.001873021,0.00000532681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935328,0.001798988,0.002751582,0.00009758726,0.00001815265,0.00001534904,0.0002107668,0.00008870655,0.001486058],"genre_scores_gemma":[0.9980161,0.0003121983,0.0006906679,0.0000228472,0.000004452963,0.000008893929,0.0001099114,0.000009275702,0.000825627],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009442492,"threshold_uncertainty_score":0.002798319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0135483483979727,"score_gpt":0.2610300121027034,"score_spread":0.2474816637047307,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}