{"id":"W2995227739","doi":"10.1101/871871","title":"ScmR, a global regulator of gene expression, quorum sensing, pH homeostasis, and virulence in <i>Burkholderia thailandensis</i>","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Burkholderia infections and melioidosis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research; University of Washington","keywords":"Regulon; Biology; Quorum sensing; Burkholderia pseudomallei; Burkholderia; Virulence; Gene; Microbiology; Genetics; Transcriptional regulation; Transcriptome; Regulation of gene expression; Gene expression; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000123065,0.0003491249,0.0002202659,0.0002708105,0.000130777,0.0002854227,0.00008323053,0.0001727907,0.0005376242],"category_scores_gemma":[0.0001252069,0.00008010695,0.0002108119,0.0002396444,0.0001780859,0.0001525037,0.0001756635,0.0002568947,0.0002418112],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001448501,"about_ca_system_score_gemma":0.0001365843,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009387343,"about_ca_topic_score_gemma":0.0008009841,"domain_scores_codex":[0.9998885,0.00001624464,0.000009288693,0.00003610927,0.00002921559,0.00002062108],"domain_scores_gemma":[0.9998688,0.00002381128,0.00004484282,0.00000800834,0.00002728259,0.00002724738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005403345,0.000005463595,0.0006054309,0.00003856889,0.00000213714,0.00002482133,0.00001203969,0.00004758682,0.9987834,0.000009950814,0.00001288074,0.0004037264],"study_design_scores_gemma":[0.00002341866,0.0004791475,0.1144065,0.00003408112,0.00003721786,0.0006663823,0.0003512639,0.003134359,0.8779197,0.00009075361,0.002833606,0.00002350556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992582,0.001398118,0.002247463,0.00009567365,0.000009032799,0.00002653399,0.002807062,0.0001045151,0.0007297568],"genre_scores_gemma":[0.9933174,0.0004357785,0.002117986,0.00006097838,0.000008068278,0.00002949644,0.003054864,0.00002235707,0.0009531012],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009387343,"threshold_uncertainty_score":0.001866519,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01208051842354331,"score_gpt":0.2298859438307113,"score_spread":0.217805425407168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}