{"id":"W2995348153","doi":"10.1111/hae.13905","title":"Measuring the impact of changing from standard half‐life (SHL) to extended half‐life (EHL) FVIII prophylaxis on health‐related quality of life (HRQoL) in boys with moderate/severe haemophilia A: Lessons learned with the CHO‐KLAT tool","year":2019,"lang":"en","type":"article","venue":"Haemophilia","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Izaak Walton Killam Health Centre; Institute for Clinical Evaluative Sciences; Dalhousie University; University of Toronto; SickKids Foundation; Hospital for Sick Children; Laurentian University","funders":"","keywords":"Medicine; Haemophilia; Bleed; Clotting factor; Haemophilia A; Quality of life (healthcare); Cohort; Pediatrics; Retrospective cohort study; Surgery; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001934492,0.000246937,0.0003100953,0.0004618572,0.0003589189,0.0006493572,0.0005185926,0.0002540382,0.00132554],"category_scores_gemma":[0.005046056,0.0001490069,0.0005197327,0.0004720384,0.000393206,0.0004385363,0.0005861195,0.0005831001,0.0001148654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008288887,"about_ca_system_score_gemma":0.0007401712,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007655971,"about_ca_topic_score_gemma":0.01299234,"domain_scores_codex":[0.9984608,0.000766383,0.0001324131,0.0001343181,0.0003140781,0.0001920276],"domain_scores_gemma":[0.9959136,0.001104203,0.001946221,0.00008953135,0.0004050545,0.0005414126],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00008019267,0.0000637045,0.9937375,0.00004003423,0.000038645,0.00003333377,0.0003837565,0.00006991441,0.00006827551,0.00001731335,0.0001736904,0.005293644],"study_design_scores_gemma":[0.000007719754,0.0005213051,0.9980988,0.0000293262,0.00002668684,0.0001832838,0.0005976861,0.000127696,0.0001263151,0.000008288092,0.0002686639,0.000004286891],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990196,0.0002955391,0.00007550263,0.00007116848,0.00000435095,0.00001723516,0.0002115457,0.000002208574,0.0003028377],"genre_scores_gemma":[0.9991009,0.0001898918,0.000354248,0.0000210749,0.000004434258,0.00001782513,0.000239284,9.471129e-7,0.00007141681],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007655971,"threshold_uncertainty_score":0.01522285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08474725006220774,"score_gpt":0.3510227390532605,"score_spread":0.2662754889910528,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}