{"id":"W2995361078","doi":"10.1158/1538-7445.panca19-c57","title":"Abstract C57: Organoid profiling identifies common responders to chemotherapy in pancreatic cancer","year":2019,"lang":"en","type":"article","venue":"Cancer Research","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Pancreatic cancer; Medicine; Oncology; Chemotherapy; Organoid; Internal medicine; Malignancy; Cancer; Cancer research; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002779483,0.0002197605,0.0005571972,0.001082951,0.0002871321,0.0008394935,0.0001687082,0.0003145663,0.002376995],"category_scores_gemma":[0.0006079893,0.0001215919,0.0003279214,0.0009820262,0.0002533949,0.0002014481,0.0005019091,0.000435895,0.0005537856],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004745977,"about_ca_system_score_gemma":0.0003135803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008917047,"about_ca_topic_score_gemma":0.001225378,"domain_scores_codex":[0.9997427,0.00003584416,0.00001923553,0.000093185,0.00006661689,0.00004247905],"domain_scores_gemma":[0.9995698,0.00009504835,0.0001323954,0.00004838436,0.00007423659,0.00008011174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002471801,0.00009487733,0.1684134,0.0001814388,0.00008537539,0.0004806813,0.0002247416,0.001035552,0.7846721,0.0002240934,0.001647865,0.04046809],"study_design_scores_gemma":[0.00007220057,0.001696705,0.7113194,0.00006536833,0.0002617732,0.00328524,0.0008371496,0.005717402,0.2609044,0.0007891218,0.01498428,0.00006693337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896526,0.001028598,0.003418165,0.0002238415,0.00002504329,0.00007677833,0.003628548,0.0001607167,0.00178582],"genre_scores_gemma":[0.988441,0.0005803835,0.004305026,0.00023936,0.00001491258,0.00008028583,0.004674292,0.00005667305,0.001607991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002376995,"threshold_uncertainty_score":0.007951856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09068682066675557,"score_gpt":0.4678894139888519,"score_spread":0.3772025933220964,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}