{"id":"W2995421143","doi":"10.1139/gen-2019-0096","title":"A linear-amplification VDJ-seq technique for quantification of immunoglobulin and T cell receptor diversity","year":2019,"lang":"en","type":"article","venue":"Genome","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Biology; Molecular biology; V(D)J recombination; Gene; Recombination; Recombination-activating gene; Gene rearrangement; T-cell receptor; CRISPR; Genetics; Gene duplication; T cell; Immune system","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001403162,0.00115665,0.001050289,0.00144839,0.001047635,0.001199192,0.000959361,0.001304316,0.00368837],"category_scores_gemma":[0.002168092,0.0005989145,0.00102432,0.001012453,0.0007234659,0.000620221,0.001040843,0.001853834,0.002325378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005268905,"about_ca_system_score_gemma":0.0005500402,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001051356,"about_ca_topic_score_gemma":0.004222975,"domain_scores_codex":[0.9981542,0.0002070732,0.0001194763,0.0007903198,0.0005802918,0.000148598],"domain_scores_gemma":[0.9989517,0.0003916394,0.0001598379,0.0001416508,0.0002779256,0.00007727592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001102972,0.00004681119,0.00172621,0.0004217337,0.00008459453,0.00008213865,0.0001982274,0.0007758371,0.9848165,0.0005708778,0.0008447807,0.01032193],"study_design_scores_gemma":[0.0000241385,0.0001710749,0.00920748,0.0000687078,0.000120831,0.0002769146,0.0001204871,0.01769903,0.9568254,0.0009484823,0.01444819,0.00008915054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.2297961,0.002770131,0.7296889,0.0002305834,0.0004993737,0.0008778637,0.02057747,0.006968662,0.008590889],"genre_scores_gemma":[0.2382846,0.001379939,0.7266809,0.001029092,0.0001217946,0.002053475,0.02009764,0.002648906,0.007703574],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.00368837,"threshold_uncertainty_score":0.01233882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01716342362270009,"score_gpt":0.2238103059225019,"score_spread":0.2066468822998018,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}