{"id":"W2995599101","doi":"10.1093/ibd/izz298","title":"Antibiotic Cocktail for Pediatric Acute Severe Colitis and the Microbiome: The PRASCO Randomized Controlled Trial","year":2019,"lang":"en","type":"article","venue":"Inflammatory Bowel Diseases","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation","funders":"Leona M. and Harry B. Helmsley Charitable Trust","keywords":"Medicine; Metronidazole; Microbiome; Randomized controlled trial; Antibiotics; Internal medicine; Ulcerative colitis; Amoxicillin; Colitis; Gastroenterology; Disease; Bioinformatics; Microbiology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002701378,0.001148979,0.003729998,0.0004816295,0.0004309714,0.001211424,0.0007672018,0.001703072,0.006017675],"category_scores_gemma":[0.004572276,0.0004528212,0.002997918,0.0006142363,0.000972619,0.001085612,0.0006021871,0.002323905,0.0004904788],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000767593,"about_ca_system_score_gemma":0.00160896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009921626,"about_ca_topic_score_gemma":0.001618645,"domain_scores_codex":[0.9982187,0.001169834,0.0001394262,0.0002094469,0.0001112349,0.0001512896],"domain_scores_gemma":[0.997001,0.001121058,0.00104945,0.0002073083,0.0001746014,0.0004465892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9842424,0.001294065,0.001523206,0.001622948,0.002082628,0.00004187395,0.00002472902,0.0001884406,0.0004475616,0.0001378764,0.0005540081,0.007840208],"study_design_scores_gemma":[0.9607691,0.03143773,0.003601791,0.0002809132,0.002489415,0.00005638505,0.00003493253,0.0003032279,0.0001452074,0.0001547247,0.0007124511,0.00001418202],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9610171,0.03083943,0.0005592531,0.001911129,0.001054022,0.001894538,0.001100012,0.0001118596,0.001512716],"genre_scores_gemma":[0.9808546,0.008425959,0.002021829,0.001550836,0.0008330809,0.004207981,0.0008931408,0.0000205554,0.001191918],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006017675,"threshold_uncertainty_score":0.02013117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003101728507709973,"score_gpt":0.2150516747474581,"score_spread":0.2119499462397481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}