{"id":"W2995658490","doi":"10.1007/s00262-019-02453-2","title":"The effect of antibiotics on clinical outcomes in immune-checkpoint blockade: a systematic review and meta-analysis of observational studies","year":2019,"lang":"en","type":"review","venue":"Cancer Immunology Immunotherapy","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":150,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Medicine; Antibiotics; Internal medicine; Oncology; Meta-analysis; Observational study; Hazard ratio; Proportional hazards model; Confidence interval; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaepi_narrow","metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.0106606,0.00242457,0.01613009,0.003340703,0.0005072656,0.002918289,0.001930421,0.002453565,0.002562128],"category_scores_gemma":[0.0284532,0.001519044,0.0340826,0.005322578,0.0007902617,0.001739968,0.001744878,0.002580465,0.0002493197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00142378,"about_ca_system_score_gemma":0.002444908,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006211074,"about_ca_topic_score_gemma":0.01278501,"domain_scores_codex":[0.9901981,0.003948492,0.003403773,0.0012433,0.0008719008,0.0003344456],"domain_scores_gemma":[0.9796528,0.01566724,0.003012716,0.0007072945,0.0007644185,0.0001955539],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.002993496,0.00002947472,0.009529784,0.2079326,0.7659888,0.0001188042,0.00006387093,0.0004423381,0.0002779315,0.0001029428,0.0004887354,0.01203115],"study_design_scores_gemma":[0.0005140891,0.0001442287,0.006728812,0.008685544,0.9824252,0.00007535746,0.00003868541,0.0001152509,0.00008951969,0.0001662685,0.0009948519,0.0000222649],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005647286,0.9931953,0.0003888824,0.0001026866,0.0001116963,0.00005850163,0.0003779063,0.00001217726,0.0001055761],"genre_scores_gemma":[0.2265549,0.7686465,0.002034404,0.001030525,0.0003141137,0.0002639337,0.0008832654,0.00003516348,0.0002373041],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9975754,"threshold_uncertainty_score":0.05637932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2622906366493449,"score_gpt":0.4919036307089502,"score_spread":0.2296129940596053,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}