{"id":"W2995676930","doi":"10.1039/c9bm01401b","title":"A Trojan horse biomimetic delivery strategy using mesenchymal stem cells for PDT/PTT therapy against lung melanoma metastasis","year":2019,"lang":"en","type":"article","venue":"Biomaterials Science","topic":"Nanoplatforms for cancer theranostics","field":"Engineering","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Scarborough Hospital; University of Toronto; Toronto Public Health","funders":"Natural Science Foundation of Zhejiang Province; National Natural Science Foundation of China","keywords":"Mesenchymal stem cell; Photodynamic therapy; Homing (biology); Cancer research; Photothermal therapy; Metastasis; Melanoma; Drug delivery; Phototoxicity; Chemistry; Medicine; Cancer; Pathology; Nanotechnology; Materials science; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009595006,0.0003656416,0.0004633026,0.000362811,0.0002003237,0.0003984313,0.0006866645,0.0001155493,0.00008793221],"category_scores_gemma":[0.000008046411,0.0003155483,0.0001333271,0.0007333356,0.0002230081,0.0007736858,0.00007188017,0.00003364604,0.00006680193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003088576,"about_ca_system_score_gemma":0.0002229545,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003810305,"about_ca_topic_score_gemma":0.000002982599,"domain_scores_codex":[0.9976959,0.00003554537,0.0005068994,0.0005115623,0.0004334512,0.0008166231],"domain_scores_gemma":[0.9989553,0.00008645122,0.0001318001,0.000524872,0.0001235151,0.0001780415],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008275707,0.000019922,0.00004794036,0.0001050535,0.00005626552,0.000004248621,0.000147338,0.002838659,0.9932248,0.00005998604,0.00003183341,0.003381172],"study_design_scores_gemma":[0.0008698042,0.0001579573,0.00006305001,0.00004898398,0.00003225975,0.000007618247,0.0001335714,0.03209943,0.9657438,0.00004469035,0.0003779733,0.0004208841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925326,0.0007947814,0.001970827,0.000004379086,0.003019404,0.001080214,0.0002622134,0.0002517521,0.00008380144],"genre_scores_gemma":[0.9963279,0.000137198,0.003235768,0.00003093079,0.0001218288,0.00003670303,0.000008221864,0.00007156919,0.00002991722],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02926077,"threshold_uncertainty_score":0.9999297,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02754341492486167,"score_gpt":0.2482583171503501,"score_spread":0.2207149022254885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}