{"id":"W2995750067","doi":"10.1128/msphere.00796-19","title":"Blocks in Tricarboxylic Acid Cycle of Salmonella enterica Cause Global Perturbation of Carbon Storage, Motility, and Host-Pathogen Interaction","year":2019,"lang":"en","type":"article","venue":"mSphere","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Regina","funders":"Deutsche Forschungsgemeinschaft","keywords":"Fumarase; Citric acid cycle; Salmonella enterica; Pentose phosphate pathway; Biochemistry; Biology; Glycolysis; Glycogen; Tricarboxylic acid; Metabolic pathway; Metabolism; Fumarate reductase; Metabolome; Microbiology; Mitochondrion; Enzyme; Succinate dehydrogenase; Metabolite; Escherichia coli","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006516124,0.0001021445,0.0001773974,0.00002452695,0.000006912629,0.000004918973,0.00009498224,0.0002211207,0.00001912032],"category_scores_gemma":[0.00002524049,0.00009878696,0.00003814084,0.000110056,0.00004906139,0.000001782836,0.0001172281,0.00005987752,6.553393e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001923775,"about_ca_system_score_gemma":0.00002463508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000156505,"about_ca_topic_score_gemma":0.0001150519,"domain_scores_codex":[0.9993212,0.00004149822,0.0002179155,0.0002372453,0.00006468986,0.0001174654],"domain_scores_gemma":[0.9995622,0.000004279924,0.0001229315,0.0002367479,0.00004785477,0.00002595346],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001209339,0.00007282726,0.04998513,0.00002926448,0.00002199243,9.504039e-7,0.00003111278,0.00002466665,0.94704,0.000006600362,0.000007144413,0.002659427],"study_design_scores_gemma":[0.0009911053,0.0009553549,0.1479075,0.00003599668,0.00002790462,0.0000169364,0.0001755644,0.001136755,0.8478456,0.00007558233,0.0006643891,0.0001672859],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981627,0.0006398385,0.00001219307,0.00004584158,0.0001354719,0.0001716508,0.00003611348,0.000004808111,0.0007913247],"genre_scores_gemma":[0.9995607,0.0001618802,0.0001271519,0.00001491742,0.00002803672,0.000003851343,0.0000226174,0.000007650617,0.00007326254],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09919436,"threshold_uncertainty_score":0.4028415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005649223017620116,"score_gpt":0.2274222310811777,"score_spread":0.2217730080635575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}