{"id":"W2995792793","doi":"10.1126/sciimmunol.aax1027","title":"Early-life programming of mesenteric lymph node stromal cell identity by the lymphotoxin pathway regulates adult mucosal immunity","year":2019,"lang":"en","type":"article","venue":"Science Immunology","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Calgary; University of Toronto","funders":"Canadian Institutes of Health Research; Princess Margaret Cancer Foundation","keywords":"Biology; Immunology; Lymphotoxin; Immune system; Mesenteric lymph nodes; Immunoglobulin A; Stromal cell; Antibody; Immunoglobulin G; Cancer research","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001132282,0.0001979542,0.0001850545,0.000180673,0.0001187775,0.0003378485,0.0001536387,0.000232433,0.0008727529],"category_scores_gemma":[0.0001481947,0.00008492645,0.0001520741,0.0000614351,0.0002175934,0.0002662506,0.0002595695,0.0005134064,0.0002169474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002714521,"about_ca_system_score_gemma":0.0001679354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002517027,"about_ca_topic_score_gemma":0.0007601471,"domain_scores_codex":[0.9998966,0.00002013522,0.00000639973,0.0000287348,0.00001478303,0.0000332773],"domain_scores_gemma":[0.999874,0.00001323236,0.0000412418,0.000009357945,0.00001389294,0.00004820019],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001188086,0.0000136918,0.002096782,0.0000166418,0.000002246469,0.00008759412,0.00003525798,0.00003577591,0.9954125,0.0001641549,0.00002054768,0.0019961],"study_design_scores_gemma":[0.00003337215,0.0007893863,0.1725311,0.00003964303,0.00003056533,0.0006472282,0.0004975148,0.001293496,0.8194926,0.0004099612,0.004217193,0.00001793209],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993982,0.001616852,0.003101281,0.00008161851,0.00001752887,0.000009763544,0.0001867499,0.00003971029,0.0009643465],"genre_scores_gemma":[0.9956949,0.0008017485,0.001418303,0.0000479303,0.000009271106,0.00001866375,0.000165933,0.00001156134,0.001831665],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008727529,"threshold_uncertainty_score":0.002919674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0112522645630388,"score_gpt":0.278470840071374,"score_spread":0.2672185755083352,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}