{"id":"W2995858855","doi":"10.3324/haematol.2019.226795","title":"The novel L-nucleoside analogue, 5-Fluorotroxacitabine, displays potent efficacy against acute myeloid leukemia","year":2019,"lang":"en","type":"letter","venue":"Haematologica","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"Myeloid leukemia; Nucleoside analogue; Medicine; Nucleoside; Leukemia; Myeloid; Cancer research; Pharmacology; Chemistry; Immunology; Stereochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.0008418379,0.001460726,0.002656223,0.0004837073,0.0008456334,0.0003352303,0.00218821,0.002781925,0.0001959715],"category_scores_gemma":[0.001125,0.0008740009,0.00120209,0.0008520112,0.001037888,0.0001680286,0.001089865,0.008538342,0.004014306],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002069798,"about_ca_system_score_gemma":0.001798482,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001226526,"about_ca_topic_score_gemma":0.0000149564,"domain_scores_codex":[0.9914566,0.0003566212,0.001495563,0.001922616,0.002096814,0.002671775],"domain_scores_gemma":[0.9925117,0.002275348,0.0007723335,0.003504141,0.0005469366,0.0003894984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000536741,0.0001111809,0.0001904928,0.0004669383,0.001415062,0.01037396,0.00006043347,0.00001494927,0.0028299,0.0003258344,0.9807413,0.002933195],"study_design_scores_gemma":[0.004056327,0.0005787181,0.003570845,0.0005753788,0.0008538472,0.004121048,0.00005708946,0.0008525116,0.0006879105,0.00007095908,0.9835021,0.001073229],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.03997737,0.001871241,0.0005395714,0.9155141,0.001545388,0.006023708,0.0006518965,0.0008089071,0.0330678],"genre_scores_gemma":[0.02010106,0.004897733,0.003268696,0.9106417,0.005260787,0.0007833599,0.005533484,0.0006529969,0.0488602],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01987631,"threshold_uncertainty_score":0.9998142,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02664574634651069,"score_gpt":0.2819097248006672,"score_spread":0.2552639784541565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}