{"id":"W2996011646","doi":"10.1167/tvst.8.6.36","title":"Topical Brimonidine or Intravitreal BDNF, CNTF, or bFGF Protect Cones Against Phototoxicity","year":2019,"lang":"en","type":"article","venue":"Translational Vision Science & Technology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"European Regional Development Fund; Allergan; Instituto de Salud Carlos III; Ministerio de Economía y Competitividad","keywords":"Ciliary neurotrophic factor; Brimonidine; Basic fibroblast growth factor; Ophthalmology; Phototoxicity; Retina; Neurotrophic factors; Erg; Medicine; Electroretinography; Retinal degeneration; Chemistry; Retinal; Anatomy; Growth factor; Internal medicine; Biology; Neuroscience; Glaucoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001115915,0.0005881988,0.0002771298,0.0002609787,0.0001489462,0.0002002075,0.000221058,0.0004113104,0.001464784],"category_scores_gemma":[0.00006583526,0.0001169645,0.0002680434,0.00008342369,0.0002169564,0.0002511255,0.0001326137,0.0004881968,0.0003527475],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002589182,"about_ca_system_score_gemma":0.0003620662,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001594742,"about_ca_topic_score_gemma":0.002541733,"domain_scores_codex":[0.999885,0.00000869691,0.000007928729,0.00002827581,0.00003463645,0.00003534008],"domain_scores_gemma":[0.9999158,0.000006345641,0.00002825,0.000009468162,0.00001350882,0.00002660233],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001231117,0.00004587994,0.00009750166,0.00003201818,0.000002604325,0.00003603466,0.00000569955,0.00001380476,0.9989862,0.00001378551,0.00002057458,0.0006228031],"study_design_scores_gemma":[0.00003536389,0.002344618,0.005090018,0.00001719489,0.00002699335,0.0003646153,0.00004013196,0.0003327974,0.9906648,0.00001866669,0.001060081,0.00000462961],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941402,0.002457982,0.001551911,0.00008123706,0.00004381194,0.00008977401,0.0002489804,0.0001068496,0.001279245],"genre_scores_gemma":[0.9902473,0.002243906,0.002506438,0.00007383312,0.00001742072,0.00008856376,0.0002916082,0.00001865833,0.004512238],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001594742,"threshold_uncertainty_score":0.004900217,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01162383413215443,"score_gpt":0.3000743326552452,"score_spread":0.2884504985230908,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}