{"id":"W2996011646","doi":"10.1167/tvst.8.6.36","title":"Topical Brimonidine or Intravitreal BDNF, CNTF, or bFGF Protect Cones Against Phototoxicity","year":2019,"lang":"en","type":"article","venue":"Translational Vision Science & Technology","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"European Regional Development Fund; Allergan; Instituto de Salud Carlos III; Ministerio de Economía y Competitividad","keywords":"Ciliary neurotrophic factor; Brimonidine; Basic fibroblast growth factor; Ophthalmology; Phototoxicity; Retina; Neurotrophic factors; Erg; Medicine; Electroretinography; Retinal degeneration; Chemistry; Retinal; Anatomy; Growth factor; Internal medicine; Biology; Neuroscience; Glaucoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002994633,0.000165325,0.0001769979,0.0002811989,0.000175958,0.00003655627,0.0004782027,0.0002363033,0.0002557707],"category_scores_gemma":[0.0001338785,0.0001169696,0.00005226024,0.000867582,0.0006663103,0.00002220312,0.00009432358,0.0001459675,0.00006475936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001686393,"about_ca_system_score_gemma":0.0004176572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006205227,"about_ca_topic_score_gemma":0.0000385416,"domain_scores_codex":[0.9984174,0.00002069114,0.0002714596,0.0005786666,0.0003679024,0.0003438663],"domain_scores_gemma":[0.999409,0.00002202925,0.00006864576,0.0002877343,0.0001376336,0.00007498442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006118983,0.00008466966,0.01247046,0.00001437604,0.000009674286,0.000005726356,0.00003362634,0.00005399891,0.958267,0.001083447,0.0001201737,0.02724499],"study_design_scores_gemma":[0.002386305,0.001889069,0.03948081,0.00005480217,0.00001045852,0.00008112408,0.0001795714,0.001410285,0.8933647,0.00204358,0.05847387,0.0006254141],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920739,0.00007372138,0.002175138,0.002469283,0.0001255161,0.0005355277,0.000007760249,0.00005810289,0.002481062],"genre_scores_gemma":[0.9959038,0.00006469475,0.002570862,0.0002839475,0.00003214839,0.00003355066,0.00003189364,0.000009979388,0.001069146],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06490225,"threshold_uncertainty_score":0.4769882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01162383413215443,"score_gpt":0.3000743326552452,"score_spread":0.2884504985230908,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}