{"id":"W2996047951","doi":"10.15252/embr.201948441","title":"Characterization of the c10orf76‐PI4KB complex and its necessity for Golgi PI4P levels and enterovirus replication","year":2019,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Victoria","funders":"H2020 Excellent Science; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; European Commission; Government of Canada; National Institutes of Health; Michael Smith Health Research BC; Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"Golgi apparatus; Biology; Cell biology; Viral replication; Replication factor C; Phosphorylation; Origin recognition complex; Biochemistry; Virus; DNA replication; Control of chromosome duplication; Genetics; Eukaryotic DNA replication; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001574309,0.00006715159,0.00009353501,0.00001137821,0.00004273009,0.000009206687,0.00003550389,0.00006940553,0.00001254643],"category_scores_gemma":[0.00002032079,0.00005449962,0.00003665105,0.00002639717,0.00002241839,0.000005939099,0.00002877838,0.00002406062,2.608412e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003286754,"about_ca_system_score_gemma":0.00001631707,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005594613,"about_ca_topic_score_gemma":0.000006850595,"domain_scores_codex":[0.9994093,0.00001473035,0.0001911607,0.0002531742,0.00006239984,0.00006922871],"domain_scores_gemma":[0.9994271,0.000003176387,0.0001926003,0.0002938917,0.00006150694,0.00002169595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001951674,0.00001215119,0.06946515,0.0000491202,0.000009363506,3.942432e-7,0.00004292385,4.430123e-7,0.9298918,0.00003373279,0.000006855821,0.0004685857],"study_design_scores_gemma":[0.0001406541,0.00004305833,0.4906213,0.000009936699,0.00001265318,0.00002389662,0.000005130828,0.00009245829,0.4968812,0.00003561334,0.01208345,0.00005071517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968305,0.0001007731,0.002292032,0.00008492955,0.000105944,0.0004044485,0.00002868681,0.000004483524,0.0001482318],"genre_scores_gemma":[0.9982557,0.00002878691,0.00004032496,0.00008827871,0.00004063589,0.00001084638,0.001110681,0.000008072198,0.000416657],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4330106,"threshold_uncertainty_score":0.222243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01865159247620072,"score_gpt":0.2432698870128656,"score_spread":0.2246182945366649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}