{"id":"W2996085778","doi":"10.1136/annrheumdis-2019-216807","title":"Response to: ‘Development and initial validation of diagnostic gene signatures for systemic lupus erythematosus' by Wang et al","year":2019,"lang":"en","type":"letter","venue":"Annals of the Rheumatic Diseases","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Western Hospital; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Medicine; Systemic disease; Systemic lupus; Systemic lupus erythematosus; Immunology; Computational biology; Internal medicine; Immunopathology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005424167,0.001021628,0.001929767,0.001356093,0.004829852,0.005052783,0.002005986,0.05408087,0.006956819],"category_scores_gemma":[0.03928534,0.001018517,0.001406832,0.001063673,0.003356857,0.003185485,0.002434396,0.04052603,0.009634721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00479143,"about_ca_system_score_gemma":0.005141823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006082329,"about_ca_topic_score_gemma":0.0100706,"domain_scores_codex":[0.9945133,0.00140229,0.0007658235,0.000718708,0.001639521,0.0009604113],"domain_scores_gemma":[0.983337,0.008511974,0.001181074,0.0005569526,0.004208556,0.002204564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000793812,0.00003246518,0.0007173905,0.00004953815,0.00001595001,0.0007190158,0.0001067743,0.00003415126,0.0001520073,0.0004867639,0.9937521,0.003854446],"study_design_scores_gemma":[0.000351043,0.0001722107,0.003742477,0.0004675057,0.00008710269,0.002409278,0.001217077,0.0007620943,0.0006802063,0.005648011,0.9843072,0.0001558527],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0002865738,0.0003736686,0.0000678291,0.978422,0.01994193,0.00001465843,0.0001067176,0.00003376189,0.0007528823],"genre_scores_gemma":[0.00193823,0.0003171634,0.0001469198,0.9728873,0.02169724,0.00004012616,0.00006647396,0.00002418698,0.002882308],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.05408087,"threshold_uncertainty_score":0.03476435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04150712307329527,"score_gpt":0.3417976108696371,"score_spread":0.3002904877963418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}