{"id":"W2996147814","doi":"10.1634/theoncologist.2019-0437","title":"Intergroup Randomized Phase III Study of Postoperative Oxaliplatin, 5-Fluorouracil, and Leucovorin Versus Oxaliplatin, 5-Fluorouracil, Leucovorin, and Bevacizumab for Patients with Stage II or III Rectal Cancer Receiving Preoperative Chemoradiation: A Trial of the ECOG-ACRIN Research Group (E5204)","year":2019,"lang":"en","type":"article","venue":"The Oncologist","topic":"Colorectal Cancer Surgical Treatments","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"National Cancer Institute; National Institutes of Health; American College of Radiology Imaging Network; Canadian Cancer Society Research Institute; NRG Oncology; ECOG-ACRIN Cancer Research Group; Sanofi","keywords":"Medicine; Bevacizumab; Oxaliplatin; Fluorouracil; Colorectal cancer; Clinical endpoint; Surgery; Neutropenia; Internal medicine; Leukopenia; Chemotherapy; Randomized controlled trial; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002152423,0.0004354668,0.001647653,0.000123887,0.0005440682,0.00005725194,0.0002984379,0.0001598271,0.0002558892],"category_scores_gemma":[0.001347601,0.0002155178,0.0001607815,0.0005807879,0.0008544412,0.0002843846,0.0004883021,0.0005458115,0.000001226824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007238679,"about_ca_system_score_gemma":0.0004730584,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003314737,"about_ca_topic_score_gemma":0.004946383,"domain_scores_codex":[0.9957384,0.001233137,0.0009710043,0.000713272,0.0008753574,0.0004687589],"domain_scores_gemma":[0.993757,0.003970117,0.0006921103,0.0006055849,0.000834507,0.0001406417],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9631411,0.00327413,0.009449531,0.0001089375,0.001087065,0.000008812956,0.01460023,0.00004296498,0.0003376506,0.00008403281,0.00009150238,0.007774009],"study_design_scores_gemma":[0.9088368,0.0716545,0.007869191,0.0002900379,0.0006263073,0.000007662391,0.008168536,0.0007095406,0.001213472,0.00001898971,0.0003210235,0.0002839557],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9801733,0.0002149208,0.00001092145,0.0005820519,0.0005142153,0.01753097,0.0002090375,0.00002747892,0.0007370259],"genre_scores_gemma":[0.9951565,0.000135955,0.0002093948,0.00004064492,0.0001221146,0.002343431,0.00004635016,0.00004455581,0.001901096],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06838037,"threshold_uncertainty_score":0.8788559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06494311937460169,"score_gpt":0.3910673084248891,"score_spread":0.3261241890502874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}