{"id":"W2996147814","doi":"10.1634/theoncologist.2019-0437","title":"Intergroup Randomized Phase III Study of Postoperative Oxaliplatin, 5-Fluorouracil, and Leucovorin Versus Oxaliplatin, 5-Fluorouracil, Leucovorin, and Bevacizumab for Patients with Stage II or III Rectal Cancer Receiving Preoperative Chemoradiation: A Trial of the ECOG-ACRIN Research Group (E5204)","year":2019,"lang":"en","type":"article","venue":"The Oncologist","topic":"Colorectal Cancer Surgical Treatments","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"National Cancer Institute; National Institutes of Health; American College of Radiology Imaging Network; Canadian Cancer Society Research Institute; NRG Oncology; ECOG-ACRIN Cancer Research Group; Sanofi","keywords":"Medicine; Bevacizumab; Oxaliplatin; Fluorouracil; Colorectal cancer; Clinical endpoint; Surgery; Neutropenia; Internal medicine; Leukopenia; Chemotherapy; Randomized controlled trial; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002863468,0.001932512,0.00188628,0.0004380638,0.0004137174,0.001180217,0.001097304,0.001870107,0.007611367],"category_scores_gemma":[0.002069211,0.0006855759,0.001696338,0.0004756119,0.0009436453,0.0008513425,0.0005119704,0.003175391,0.001189522],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001044887,"about_ca_system_score_gemma":0.001765935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001442321,"about_ca_topic_score_gemma":0.004076569,"domain_scores_codex":[0.9990786,0.0005879441,0.00003982452,0.0001212337,0.00005358693,0.0001187683],"domain_scores_gemma":[0.9988732,0.0002290957,0.0003229461,0.00009083435,0.00007773543,0.0004062315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.975007,0.007981308,0.0007286161,0.0003132891,0.0006550266,0.00002884006,0.00004645811,0.00038186,0.002081663,0.000162122,0.002016801,0.01059705],"study_design_scores_gemma":[0.9641003,0.03321949,0.001095942,0.0000224044,0.000198601,0.00001970871,0.00001469217,0.0002877574,0.0001937525,0.0000937927,0.0007454078,0.000008145365],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9693018,0.004427628,0.001506406,0.001926883,0.001276193,0.01220998,0.004055614,0.0002205353,0.005074933],"genre_scores_gemma":[0.9607985,0.002830991,0.003461375,0.004231865,0.0005923379,0.01663353,0.003992169,0.0000544219,0.007404763],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007611367,"threshold_uncertainty_score":0.02546257,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06494311937460169,"score_gpt":0.3910673084248891,"score_spread":0.3261241890502874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}