{"id":"W2996365559","doi":"10.2147/copd.s220850","title":"<p>Efficacy and Safety of Budesonide/Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Formulated Using Co-Suspension Delivery Technology in Japanese Patients with COPD: A Subgroup Analysis of the KRONOS Study</p>","year":2019,"lang":"en","type":"article","venue":"International Journal of COPD","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Daiichi Sankyo Europe; Novartis Pharma; Boehringer Ingelheim Japan; Sunovion; Shionogi; Chiesi Farmaceutici; Sanofi; Mylan; GlaxoSmithKline; Teva Pharmaceutical Industries; AstraZeneca","keywords":"Formoterol Fumarate; Formoterol; Medicine; Metered-dose inhaler; Budesonide; Dry-powder inhaler; COPD; Inhaler; Anesthesia; Internal medicine; Asthma; Inhalation","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002342131,0.00100924,0.002075666,0.0004113717,0.0004426065,0.0008626324,0.0003537432,0.0006799368,0.0009818499],"category_scores_gemma":[0.001125123,0.0003887153,0.004922377,0.0005498278,0.0005318137,0.0004645207,0.0003868264,0.0006434642,0.0001628522],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005801921,"about_ca_system_score_gemma":0.001188813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001657142,"about_ca_topic_score_gemma":0.005434082,"domain_scores_codex":[0.9991049,0.0003298211,0.0001886623,0.0001659797,0.0001089437,0.0001016311],"domain_scores_gemma":[0.99909,0.0001728636,0.0003570062,0.0001230824,0.00009221143,0.0001648155],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6843468,0.002900244,0.2025219,0.003789208,0.03462399,0.0005083684,0.0005013034,0.0006614978,0.03042874,0.0001063018,0.001477183,0.03813452],"study_design_scores_gemma":[0.1787116,0.1087198,0.5899214,0.0003687119,0.1068433,0.001140765,0.0008943825,0.001461152,0.006394174,0.000324609,0.005017223,0.0002029275],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946237,0.00387709,0.0001863618,0.00009881377,0.00003950465,0.0002948914,0.0004756818,0.000008239756,0.0003957484],"genre_scores_gemma":[0.997429,0.0008804696,0.0002668367,0.0002134476,0.00006195704,0.0002866499,0.0006281906,0.000005993379,0.0002276085],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002342131,"threshold_uncertainty_score":0.01238656,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01209921044744522,"score_gpt":0.2879147394961751,"score_spread":0.2758155290487299,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}