{"id":"W2996489767","doi":"10.3390/jcm8122214","title":"Liposomal Lapatinib in Combination with Low-Dose Photodynamic Therapy for the Treatment of Glioma","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Medicine","topic":"Photodynamic Therapy Research Studies","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network; Princess Margaret Cancer Centre","funders":"National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health; Ontario Ministry of Health and Long-Term Care","keywords":"Lapatinib; Medicine; Photodynamic therapy; In vivo; U87; Glioma; Cancer research; Protoporphyrin IX; Epidermal growth factor receptor; Pharmacology; Cancer; Oncology; Trastuzumab; Internal medicine; Breast cancer; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002006585,0.0003537463,0.0003570147,0.0003251756,0.0001126159,0.0002925032,0.0002802452,0.000263337,0.001099889],"category_scores_gemma":[0.0001129454,0.000107186,0.0002154304,0.0002170464,0.0002139259,0.0002976836,0.0003168221,0.0004887051,0.0002269633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003179013,"about_ca_system_score_gemma":0.0002166457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004550844,"about_ca_topic_score_gemma":0.0006992256,"domain_scores_codex":[0.999927,0.0000172808,0.000005657299,0.00001428274,0.00001865481,0.00001720772],"domain_scores_gemma":[0.9999651,0.000004781091,0.000009959253,0.000002821896,0.000003890419,0.00001333618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.002018167,0.0006706829,0.0003247134,0.00033518,0.00005507981,0.0002012464,0.0000558022,0.0007818419,0.9585831,0.0001965371,0.0003754268,0.03640227],"study_design_scores_gemma":[0.001600455,0.01524255,0.004245735,0.00004368343,0.0001979405,0.001624277,0.00005127383,0.004450684,0.9636077,0.0001563699,0.008748055,0.00003118103],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984557,0.008444234,0.004162327,0.0002738458,0.00006510143,0.0001908149,0.0001200394,0.0001295171,0.002056993],"genre_scores_gemma":[0.9946337,0.00237489,0.001972959,0.00005098004,0.00002106634,0.00006453343,0.000149669,0.00001606896,0.0007161224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001099889,"threshold_uncertainty_score":0.003679454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04660382038975074,"score_gpt":0.4282265240919949,"score_spread":0.3816227037022442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}