{"id":"W2996510310","doi":"10.1016/j.jmb.2019.12.012","title":"Recent Insights into Beta-cell Exocytosis in Type 2 Diabetes","year":2019,"lang":"en","type":"review","venue":"Journal of Molecular Biology","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health; Juvenile Diabetes Research Foundation International","keywords":"Exocytosis; Type 2 diabetes; Diabetes mellitus; Population; Insulin; Biology; Type 1 diabetes; Beta cell; Cell biology; Medicine; Bioinformatics; Immunology; Endocrinology; Islet; Secretion","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009089654,0.001423362,0.002041386,0.001969818,0.000238731,0.001602121,0.0009088213,0.001396881,0.003140493],"category_scores_gemma":[0.001038681,0.000368492,0.0005906916,0.001991384,0.000669997,0.00213937,0.001391278,0.002445845,0.001975241],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006251929,"about_ca_system_score_gemma":0.0008512203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004649092,"about_ca_topic_score_gemma":0.0008312783,"domain_scores_codex":[0.9998187,0.00002612116,0.00003311035,0.00003757094,0.00005882408,0.0000255972],"domain_scores_gemma":[0.9995055,0.0002494291,0.00006320217,0.00001271693,0.0001048255,0.00006435873],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002462023,0.00006841428,0.0001670465,0.01626368,0.0001111059,0.0002385774,0.00004453326,0.0003917625,0.00257868,0.00299066,0.02862759,0.9482716],"study_design_scores_gemma":[0.00006192387,0.0001488889,0.0008759997,0.004139102,0.0002399195,0.001135324,0.00007058911,0.0001691792,0.0007543006,0.003477571,0.9888938,0.00003336175],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000616536,0.99897,0.0001148199,0.0002265702,0.0003151149,0.0000016846,0.00001018018,0.000004993272,0.0002949933],"genre_scores_gemma":[0.0003335105,0.9985977,0.0001229252,0.0001904864,0.0004418424,0.000002759431,0.00001820825,0.000001063711,0.0002915883],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003140493,"threshold_uncertainty_score":0.01050597,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.041145801481205,"score_gpt":0.3327653469960449,"score_spread":0.2916195455148399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}