{"id":"W2996552716","doi":"10.1016/j.cell.2019.11.026","title":"Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease","year":2019,"lang":"en","type":"article","venue":"Cell","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":484,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; Alberta Innovates; Damon Runyon Cancer Research Foundation; National Multiple Sclerosis Society; Howard Hughes Medical Institute","keywords":"Biology; Interleukin 17; Immunology; Inflammation; Cell biology; RAR-related orphan receptor gamma; Cytokine; Innate lymphoid cell; FOXP3; Acquired immune system; Immune system","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002655185,0.0004436739,0.0001930548,0.0003873022,0.0002222175,0.0003409567,0.00008095181,0.0002953353,0.001890829],"category_scores_gemma":[0.0001639431,0.0000889799,0.0002879353,0.0001480882,0.0002201867,0.0001681046,0.0001768937,0.0010903,0.0004423428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001301417,"about_ca_system_score_gemma":0.0002057038,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001715959,"about_ca_topic_score_gemma":0.0002518311,"domain_scores_codex":[0.9998186,0.00006561624,0.00001264995,0.00001441912,0.00004606515,0.00004276914],"domain_scores_gemma":[0.9998555,0.00002695178,0.00002571558,0.00001753291,0.00002656601,0.00004763863],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001398401,0.0007679518,0.001778095,0.0001707509,0.00003445897,0.0004226899,0.00004922425,0.0001925833,0.9558228,0.0005325474,0.001386777,0.03744369],"study_design_scores_gemma":[0.0008008517,0.007999438,0.0225266,0.00007540045,0.0001367776,0.003333382,0.0003193982,0.00234541,0.9243281,0.001702308,0.03641285,0.00001949314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9727656,0.01186679,0.004727576,0.001059577,0.0007062553,0.00009821037,0.0002033748,0.0002168773,0.008355758],"genre_scores_gemma":[0.9905626,0.003505702,0.001524878,0.0002434255,0.0002757478,0.00003971111,0.0001237949,0.00001740165,0.003706776],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001890829,"threshold_uncertainty_score":0.006325483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007569796244783693,"score_gpt":0.1910738623451584,"score_spread":0.1835040661003748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}