{"id":"W2996655455","doi":"10.29169/1927-5951.2019.09.06.6","title":"Study of Dissolution Enhancement of Furosemide by Solid Dispersion Technique Using Different Polymer","year":2019,"lang":"en","type":"article","venue":"Journal of Pharmacy and Nutrition Sciences","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Poloxamer; Dissolution; Furosemide; Poloxamer 407; Chromatography; Bioavailability; Permeation; Solubility; Chemistry; Polymer; Materials science; Chemical engineering; Pharmacology; Membrane; Organic chemistry; Medicine; Copolymer; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001297548,0.0001204499,0.0003574551,0.0001964413,0.0001543005,0.00001437782,0.000198203,0.0000597111,0.0001872034],"category_scores_gemma":[0.00001493542,0.00009238935,0.00008601043,0.0002279841,0.0002386785,0.000363935,0.00005206562,0.0002432159,0.000001293393],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000340493,"about_ca_system_score_gemma":0.00004094481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003723727,"about_ca_topic_score_gemma":0.000001399354,"domain_scores_codex":[0.9981612,0.0004122264,0.0007156496,0.000156606,0.0003806091,0.0001736905],"domain_scores_gemma":[0.9987575,0.0001640669,0.0007598132,0.00006203921,0.0001521921,0.0001043288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006530618,0.002445554,0.034385,0.0001657213,0.00005892102,0.000003720121,0.0008321083,0.00004067368,0.9604956,0.00002722155,0.0003321985,0.0005602429],"study_design_scores_gemma":[0.003388927,0.001601068,0.0004016958,0.0001668238,0.0001296853,0.00006965529,0.00283951,0.001980836,0.9881442,0.00005682043,0.001108565,0.0001121927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950132,0.003154147,0.0003805121,0.0001307087,0.0006913085,0.0005004438,0.00002250719,0.00000413592,0.0001030074],"genre_scores_gemma":[0.9988578,0.000906411,0.00004812378,0.00005572699,0.00007381047,0.000006037923,0.00000133466,0.000003789931,0.00004696604],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0339833,"threshold_uncertainty_score":0.3767529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1265984862926579,"score_gpt":0.4598550976618372,"score_spread":0.3332566113691794,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}