{"id":"W2996879362","doi":"10.1016/j.jmb.2019.12.024","title":"Structural Insights Into PfARO and Characterization of its Interaction With PfAIP","year":2019,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Malaria Research and Control","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Training Centre for Food and Beverage Supply Chain Optimisation, Australian Research Council; National Health and Medical Research Council; Canadian Institutes of Health Research; University of Adelaide; German-Israeli Foundation for Scientific Research and Development; Deutsche Forschungsgemeinschaft; European Molecular Biology Laboratory; Deutscher Akademischer Austauschdienst; Deutsche Stiftung für Herzforschung; Joachim Herz Stiftung","keywords":"Rhoptry; Biology; Plasmodium falciparum; Cell biology; Tandem repeat; Organelle; Genetics; Apicomplexa; Gene; Malaria; Immunology; Genome","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001840394,0.0003991672,0.0003195434,0.0002549731,0.0004208247,0.0003638356,0.0004564347,0.0004153508,0.004250117],"category_scores_gemma":[0.0003223557,0.0001261142,0.000518802,0.0003053774,0.0002572229,0.0004599002,0.0002579538,0.001112823,0.001012391],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003837098,"about_ca_system_score_gemma":0.0002650349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008809725,"about_ca_topic_score_gemma":0.000640299,"domain_scores_codex":[0.9998773,0.00001733603,0.000006915686,0.0000247681,0.00003300145,0.00004064985],"domain_scores_gemma":[0.999866,0.0000343815,0.00002773991,0.00001260763,0.00002148257,0.00003775137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001021634,0.0002836728,0.003875664,0.0001970993,0.00005392703,0.001405262,0.0001710429,0.002451001,0.9757572,0.003364346,0.001616913,0.009802194],"study_design_scores_gemma":[0.0001066616,0.0006394958,0.02182499,0.00004981493,0.00009610233,0.003330592,0.0004448298,0.01988499,0.8928505,0.001448594,0.05926618,0.00005721324],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9832791,0.002507994,0.006802406,0.0009989697,0.0001544231,0.00004481039,0.0009497557,0.0001321544,0.005130281],"genre_scores_gemma":[0.987874,0.001291834,0.004613767,0.0002645793,0.00005632779,0.00001938801,0.002227437,0.00002128952,0.003631416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004250117,"threshold_uncertainty_score":0.01421803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006431508847198651,"score_gpt":0.2762541451835916,"score_spread":0.269822636336393,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}