{"id":"W2996950035","doi":"10.1016/j.cell.2019.12.006","title":"In Situ Structure of an Intact Lipopolysaccharide-Bound Bacterial Surface Layer","year":2019,"lang":"en","type":"article","venue":"Cell","topic":"Advanced Electron Microscopy Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; European Research Council; National Institutes of Health; Wellcome Trust; National Institute of General Medical Sciences; Medical Research Council; Vallee Foundation","keywords":"Caulobacter crescentus; Biology; S-layer; Lipopolysaccharide; In situ; Biophysics; Cell biology; Paracrystalline; Bacteria; Layer (electronics); Bacterial cell structure; Bacterial outer membrane; Biochemistry; Crystallography; Nanotechnology; Materials science; Escherichia coli; Chemistry; Bacterial protein; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00002522654,0.00007813625,0.00009034613,0.00001336598,0.00001211178,0.000006974079,0.0001276725,0.00009867458,0.0001082977],"category_scores_gemma":[0.000001773514,0.00007717563,0.00002488455,0.00003809723,0.0000192486,0.000005524711,0.00003954124,0.00006783869,0.000005795419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009565579,"about_ca_system_score_gemma":0.0000308466,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002857224,"about_ca_topic_score_gemma":0.00006685191,"domain_scores_codex":[0.9995226,0.00001253945,0.0001116701,0.0001929658,0.00003389659,0.0001262995],"domain_scores_gemma":[0.9996266,0.00000251338,0.00005281395,0.0002707596,0.00002121394,0.00002613781],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003277854,0.00003372119,0.0002192086,0.00000881928,0.000001990809,1.681691e-7,0.00001383007,0.00004860897,0.9993796,0.00005077895,0.0001417168,0.00006879398],"study_design_scores_gemma":[0.0002052102,0.0001507447,0.0001383022,0.000002454755,0.000002257029,0.000001428407,0.00001228104,0.000006082026,0.9885634,0.0002736259,0.01055652,0.00008770784],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989441,0.00006754271,0.000346095,0.00001644313,0.00005310103,0.0001538959,0.00002295885,0.00000639885,0.0003894645],"genre_scores_gemma":[0.996397,0.00003354723,0.002817809,0.0000658374,0.00005634458,0.000001869117,0.0001011848,0.00001362273,0.0005127979],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0108162,"threshold_uncertainty_score":0.3147131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004447773672560809,"score_gpt":0.2792515233764082,"score_spread":0.2748037497038474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}