{"id":"W2996950035","doi":"10.1016/j.cell.2019.12.006","title":"In Situ Structure of an Intact Lipopolysaccharide-Bound Bacterial Surface Layer","year":2019,"lang":"en","type":"article","venue":"Cell","topic":"Advanced Electron Microscopy Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; European Research Council; National Institutes of Health; Wellcome Trust; National Institute of General Medical Sciences; Medical Research Council; Vallee Foundation","keywords":"Caulobacter crescentus; Biology; S-layer; Lipopolysaccharide; In situ; Biophysics; Cell biology; Paracrystalline; Bacteria; Layer (electronics); Bacterial cell structure; Bacterial outer membrane; Biochemistry; Crystallography; Nanotechnology; Materials science; Escherichia coli; Chemistry; Bacterial protein; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006480716,0.0001788185,0.0001369393,0.0001934702,0.000334846,0.0003263527,0.0003573615,0.0003448864,0.001395387],"category_scores_gemma":[0.0001441933,0.0002124988,0.0001523388,0.0001799497,0.0003145495,0.0003130238,0.000248397,0.0005915454,0.0002880539],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003748171,"about_ca_system_score_gemma":0.0002205378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001559378,"about_ca_topic_score_gemma":0.001310249,"domain_scores_codex":[0.999971,0.000001984358,0.000001255085,0.000008963572,0.0000091821,0.000007564054],"domain_scores_gemma":[0.9999061,0.00002087777,0.00002319156,0.00001667925,0.00001764629,0.00001544813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006708238,0.00001689354,0.0006023652,0.00004253679,0.000008682789,0.0001716518,0.00004479894,0.0006493448,0.9970932,0.0003268868,0.00009936633,0.000877218],"study_design_scores_gemma":[0.00003142669,0.0001735021,0.01640388,0.0000235422,0.00004050045,0.0008232294,0.0002243677,0.01358004,0.9636399,0.0004385451,0.004598069,0.00002288304],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9904726,0.0007553719,0.006180622,0.0001519238,0.00002608282,0.00001223744,0.0003491234,0.0001137858,0.001938396],"genre_scores_gemma":[0.9890511,0.0006247287,0.008111025,0.00005235361,0.00001438045,0.00001456262,0.0005439899,0.00004810995,0.001539838],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001559378,"threshold_uncertainty_score":0.004667997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004447773672560809,"score_gpt":0.2792515233764082,"score_spread":0.2748037497038474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}