{"id":"W2997007510","doi":"10.1073/pnas.1908654117","title":"Actin protrusions push at apical junctions to maintain E-cadherin adhesion","year":2019,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; National Institutes of Health; McMaster University","keywords":"Cadherin; Adhesion; Actin; Cell biology; Chemistry; Biology; Materials science; Composite material; Cell; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001245584,0.0002469629,0.0003855011,0.0003291461,0.0003915913,0.0007147646,0.000281987,0.0004092293,0.001192725],"category_scores_gemma":[0.0002013185,0.0003039739,0.0002389186,0.000142101,0.0002234208,0.0005353352,0.0005063415,0.00091125,0.001163689],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003825659,"about_ca_system_score_gemma":0.0002252586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004133041,"about_ca_topic_score_gemma":0.001123719,"domain_scores_codex":[0.9997949,0.00001296092,0.00001278909,0.00004176621,0.00008006111,0.00005759743],"domain_scores_gemma":[0.9997727,0.00003772338,0.0000409556,0.00003336393,0.00003840263,0.00007679491],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001101232,0.000005453676,0.0001924617,0.000007702204,0.000001491985,0.00003133218,0.000007198338,0.00002416518,0.9989574,0.00008674771,0.00002154795,0.0006534708],"study_design_scores_gemma":[0.00001150477,0.00006709505,0.01296054,0.000008671386,0.000008307812,0.0001764887,0.00005404885,0.001561829,0.982798,0.0001440654,0.002202832,0.000006581083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9869471,0.000916847,0.008858996,0.0001372615,0.00002239701,0.0000182572,0.0001812809,0.0002538469,0.002664185],"genre_scores_gemma":[0.991724,0.0004027125,0.004484035,0.00009883238,0.0000156125,0.00002150644,0.0002938405,0.00005938004,0.002900062],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001192725,"threshold_uncertainty_score":0.003990054,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02543597525440657,"score_gpt":0.2953285541253622,"score_spread":0.2698925788709557,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}