{"id":"W2997281000","doi":"10.1128/aac.01909-19","title":"Forging New Antibiotic Combinations under Iron-Limiting Conditions","year":2020,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Cystic Fibrosis Canada; Natural Sciences and Engineering Research Council of Canada; Government of Canada; Ontario Research Foundation","keywords":"Thiostrepton; Pseudomonas aeruginosa; Acinetobacter baumannii; Microbiology; Antibiotics; Biology; Pyoverdine; Pathogen; Bacteria; Gene; Biochemistry; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000504623,0.0006332576,0.001171532,0.0009442227,0.0004177747,0.0008101024,0.0006316105,0.0005061988,0.002406554],"category_scores_gemma":[0.0005564947,0.0003869966,0.0004387975,0.0005930425,0.0003839854,0.001279721,0.0007880819,0.001118833,0.001191859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003031505,"about_ca_system_score_gemma":0.0003033772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001757774,"about_ca_topic_score_gemma":0.0007833896,"domain_scores_codex":[0.9993913,0.0001276068,0.00005105676,0.0001443865,0.0001888064,0.00009677548],"domain_scores_gemma":[0.9997155,0.00006693215,0.0000654867,0.00005046674,0.00003951163,0.0000620838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008835111,0.000650417,0.001314105,0.0009488033,0.0001764289,0.0006952319,0.0002004045,0.001213246,0.8677395,0.001829415,0.002175744,0.1221731],"study_design_scores_gemma":[0.0003193697,0.006019881,0.003449269,0.0002056133,0.0003514394,0.002625376,0.000232422,0.003679576,0.8246409,0.002001737,0.1563827,0.00009165887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8749731,0.06960171,0.0273167,0.00221811,0.0009453598,0.0007827758,0.0008676863,0.001170017,0.02212469],"genre_scores_gemma":[0.9206074,0.02785072,0.04166702,0.001124093,0.0003287017,0.0003375509,0.0008728483,0.0002244736,0.006987133],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002406554,"threshold_uncertainty_score":0.008050799,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01659412019570464,"score_gpt":0.2604822864837672,"score_spread":0.2438881662880626,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}