{"id":"W2997666827","doi":"10.2337/db19-0798","title":"Interplay of Placental DNA Methylation and Maternal Insulin Sensitivity in Pregnancy","year":2019,"lang":"en","type":"article","venue":"Diabetes","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Intégré Universitaire de Santé et de Services Sociaux du Saguenay–Lac-Saint-Jean; Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; American Diabetes Association","keywords":"DNA methylation; Genomic imprinting; Biology; Offspring; Methylation; CpG site; Epigenetics; Pregnancy; Placenta; Internal medicine; Endocrinology; Genetics; Gene; Fetus; Medicine; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000137946,0.00006225539,0.00009259903,0.00003575655,0.000007118839,0.000006484615,0.00002498425,0.00006631425,0.000007507377],"category_scores_gemma":[0.0000257778,0.00006092501,0.00002061427,0.00003316611,0.00002091111,0.000003726635,0.00004581771,0.0000319793,0.000002627565],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000456437,"about_ca_system_score_gemma":0.000008137634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001206404,"about_ca_topic_score_gemma":0.00002025153,"domain_scores_codex":[0.9995501,0.0000454805,0.0001218987,0.000141071,0.00005088268,0.00009058906],"domain_scores_gemma":[0.9997948,0.00001617141,0.00005428082,0.00009396372,0.00002148419,0.00001933099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007692423,0.00001123037,0.4278167,0.00001769765,0.000004915794,1.546169e-7,0.00002492816,0.00002338403,0.5679446,0.00001156467,6.012445e-7,0.00413651],"study_design_scores_gemma":[0.0002376955,0.00007447196,0.3086872,0.00004001324,0.000002122596,1.133828e-7,0.00000963494,0.0003565323,0.6904212,0.00007959858,0.00004415951,0.00004729372],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979082,0.001583082,0.00005711808,0.00001056965,0.00006553571,0.000109178,0.00001146066,0.000002275579,0.0002525233],"genre_scores_gemma":[0.9995968,0.0001258505,0.0001663237,0.000009225419,0.0000168056,0.00000277977,0.00003157809,0.000006791924,0.00004384536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1224766,"threshold_uncertainty_score":0.248445,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004714531917268668,"score_gpt":0.2350511887108811,"score_spread":0.2303366567936124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}