{"id":"W2997672664","doi":"10.1371/journal.ppat.1008167","title":"Phosphoinositide signaling and regulation in Trypanosoma brucei: Specialized functions in a protozoan pathogen","year":2020,"lang":"en","type":"review","venue":"PLoS Pathogens","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Trypanosoma brucei; Biology; Cell biology; Signal transduction; Immune system; Cell signaling; Organelle biogenesis; Leishmania; Gene; Biochemistry; Biogenesis; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001085766,0.0003415004,0.0002430439,0.0003214445,0.0003904114,0.0007077726,0.0002409165,0.0006971867,0.001446886],"category_scores_gemma":[0.00007037134,0.0001355151,0.0001507174,0.000430647,0.0003073455,0.0003903563,0.0004207308,0.0005541109,0.0006610331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007326464,"about_ca_system_score_gemma":0.0003488395,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002383517,"about_ca_topic_score_gemma":0.002571336,"domain_scores_codex":[0.9999104,0.000007094249,0.000005826583,0.00002992076,0.00002339238,0.00002336019],"domain_scores_gemma":[0.9999579,0.000003083075,0.00001183461,0.000002034545,0.000007769721,0.00001747093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004713776,0.00007098707,0.003423824,0.0009078662,0.00001840675,0.001273798,0.0003546119,0.0003894871,0.9468966,0.007025586,0.002503863,0.03666366],"study_design_scores_gemma":[0.000144155,0.001345565,0.2750457,0.0008775921,0.0002105026,0.0128316,0.001580698,0.007351951,0.3467656,0.01430182,0.3393949,0.0001500214],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.5218412,0.4247102,0.01170463,0.003323475,0.0005528797,0.000120198,0.003706442,0.0004935474,0.03354754],"genre_scores_gemma":[0.8859807,0.09527474,0.00363666,0.0006043398,0.0003933272,0.00008512611,0.002017802,0.00003317912,0.01197413],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.002383517,"threshold_uncertainty_score":0.005315721,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07440310232142273,"score_gpt":0.3372936512576625,"score_spread":0.2628905489362398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}