{"id":"W2997795722","doi":"","title":"The Role of Templating in the Emergence of RNA from the Prebiotic Chemical Mixture","year":2017,"lang":"en","type":"article","venue":"LPICo","topic":"Origins and Evolution of Life","field":"Physics and Astronomy","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Polymerization; Nucleotide; Monomer; Chemistry; Chirality (physics); RNA; Template; Nucleobase; Nucleic acid; Chemical ligation; Stereochemistry; Combinatorial chemistry; Polymer; Nanotechnology; DNA; Symmetry breaking; Organic chemistry; Materials science; Amino acid; Biochemistry; Physics; Spontaneous symmetry breaking","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006813798,0.0002550706,0.0004363951,0.000311902,0.0009415949,0.001307571,0.0007502747,0.001001885,0.001830381],"category_scores_gemma":[0.00334649,0.000488947,0.0006399454,0.0001749784,0.002069336,0.002784379,0.0009889506,0.001001677,0.0002394475],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007630371,"about_ca_system_score_gemma":0.0006180651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000926286,"about_ca_topic_score_gemma":0.0007830163,"domain_scores_codex":[0.9997821,0.00007871679,0.00000805349,0.00004038594,0.00004867528,0.00004207367],"domain_scores_gemma":[0.9989638,0.0006833344,0.00009547279,0.0001090616,0.00003785186,0.0001103771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0002929236,0.0001517244,0.004976928,0.0001737605,0.00004883863,0.0007980889,0.0004238052,0.5584446,0.04296879,0.3800945,0.0005739353,0.01105197],"study_design_scores_gemma":[0.00008569786,0.000138453,0.001165293,0.00001948697,0.00003040405,0.0001704429,0.0001227648,0.8758318,0.01075235,0.1104935,0.001147304,0.00004253663],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9134729,0.0003859035,0.06853385,0.000815336,0.00005147529,0.00003349223,0.00005797566,0.0001290166,0.01651996],"genre_scores_gemma":[0.9932517,0.0001402409,0.005633009,0.00003467131,0.000007873479,0.00002737766,0.00001571038,0.00002931692,0.0008600336],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001830381,"threshold_uncertainty_score":0.006123185,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009380552049209071,"score_gpt":0.2520867146975156,"score_spread":0.2427061626483065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}