{"id":"W2997819432","doi":"10.1073/pnas.1912109117","title":"The circadian clock protein REVERBα inhibits pulmonary fibrosis development","year":2019,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","field":"Medicine","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Manchester Biomedical Research Centre; Medical Research Council; Versus Arthritis; Government of Canada; Asthma and Lung UK; Arthritis Research UK; National Institute for Health and Care Research; University of Manchester; Wellcome Trust; National Institute of Academic Anaesthesia; Newcastle University; National Institute for Academic Anaesthesia","keywords":"Pulmonary fibrosis; Myofibroblast; Cancer research; Idiopathic pulmonary fibrosis; Medicine; Circadian clock; Fibrosis; Bleomycin; Circadian rhythm; Cell biology; Lung; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001257096,0.0002060276,0.0002884788,0.0001819468,0.000107966,0.0002520605,0.0001567031,0.0002083637,0.001586318],"category_scores_gemma":[0.0001479538,0.0001146284,0.0001998194,0.00008845361,0.0001960312,0.00009961995,0.0001204982,0.0006233637,0.000337729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001723026,"about_ca_system_score_gemma":0.000211547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004674621,"about_ca_topic_score_gemma":0.0008137957,"domain_scores_codex":[0.9998822,0.00002718893,0.000008684072,0.0000187868,0.00002770454,0.00003548649],"domain_scores_gemma":[0.9998736,0.0000148473,0.0000305561,0.00001777967,0.00001174365,0.00005140462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001430357,0.0002070698,0.0002979262,0.00007224247,0.00002195033,0.00004819937,0.00001761415,0.0001698923,0.990671,0.0001367894,0.0003019044,0.006625006],"study_design_scores_gemma":[0.0002749649,0.003457407,0.01076285,0.00002174379,0.00004291991,0.0003317927,0.00007795412,0.002310281,0.9745281,0.0001173487,0.00806519,0.000009555307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9902526,0.004130769,0.002432153,0.0003527581,0.0002581269,0.00003299156,0.0004308185,0.0002394194,0.0018703],"genre_scores_gemma":[0.994606,0.001574994,0.0009238755,0.00009372559,0.00002740158,0.00002889983,0.0004020125,0.00002600594,0.002317141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001586318,"threshold_uncertainty_score":0.00530678,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02032810026564901,"score_gpt":0.2701572716040865,"score_spread":0.2498291713384375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}