{"id":"W2997963046","doi":"10.1096/fj.201901989r","title":"Crystal structure of proteolyzed VapBC and DNA‐bound VapBC from <i>Salmonella enterica</i> Typhimurium LT2 and VapC as a putative Ca <sup>2+</sup> ‐dependent ribonuclease","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"National Research Foundation of Korea","keywords":"Ribonuclease; DNA; Antitoxin; Biology; Salmonella enterica; Salmonella; DNA-binding domain; Biophysics; Genetics; RNA; Bacteria; Gene; Toxin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001512255,0.000239379,0.00028444,0.00004979649,0.000129528,0.00009014957,0.0002695289,0.0002800146,0.0001406425],"category_scores_gemma":[0.00003964645,0.000166902,0.00007890078,0.00006268061,0.0002713729,0.00000819295,0.0003084813,0.0003280809,0.000006658726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001325304,"about_ca_system_score_gemma":0.00009138726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009243104,"about_ca_topic_score_gemma":0.00001243189,"domain_scores_codex":[0.9987574,0.0001370782,0.0003076056,0.0003398857,0.0001770348,0.0002809505],"domain_scores_gemma":[0.9991741,0.00002249365,0.0002535731,0.0003101797,0.000102225,0.0001374011],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000550579,0.00003987398,0.0006791464,0.00001598698,0.0001765582,0.00001232895,0.0003824697,0.00006789185,0.9974375,0.0000132805,0.00009406144,0.0005303263],"study_design_scores_gemma":[0.001754365,0.0009881409,0.001148077,0.00002978544,0.0000916846,0.0005384429,0.0007281959,0.0002470139,0.991536,0.001376444,0.00131923,0.0002426596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997748,0.0008756713,0.00007149608,0.0003847538,0.0001520762,0.0003398506,0.0003357963,0.000006239151,0.00008614369],"genre_scores_gemma":[0.9985154,0.0003865749,0.0003577606,0.0002326507,0.0002554039,0.000002784428,0.00005683271,0.00002705634,0.0001655483],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005901536,"threshold_uncertainty_score":0.6806066,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004064075807606043,"score_gpt":0.2019141760202396,"score_spread":0.1978501002126336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}