{"id":"W2997963046","doi":"10.1096/fj.201901989r","title":"Crystal structure of proteolyzed VapBC and DNA‐bound VapBC from <i>Salmonella enterica</i> Typhimurium LT2 and VapC as a putative Ca <sup>2+</sup> ‐dependent ribonuclease","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"National Research Foundation of Korea","keywords":"Ribonuclease; DNA; Antitoxin; Biology; Salmonella enterica; Salmonella; DNA-binding domain; Biophysics; Genetics; RNA; Bacteria; Gene; Toxin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001241319,0.0005074102,0.0003882221,0.0001884547,0.0003484582,0.0004767014,0.0006350499,0.0004225045,0.001273276],"category_scores_gemma":[0.0002897354,0.0003357524,0.0003490224,0.0003732337,0.0002127283,0.0002065132,0.0002015517,0.0009665042,0.0002728686],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009814075,"about_ca_system_score_gemma":0.0006453887,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009429691,"about_ca_topic_score_gemma":0.00787554,"domain_scores_codex":[0.9998785,0.00001367101,0.00000529406,0.00002688581,0.00004570723,0.00003005373],"domain_scores_gemma":[0.9998381,0.00002670982,0.0000301321,0.000006199659,0.00004078965,0.00005806408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007999041,0.0002171127,0.006812592,0.0005060293,0.0001931593,0.001046455,0.0003393152,0.00341766,0.9782642,0.0007036786,0.003536254,0.004163667],"study_design_scores_gemma":[0.001325664,0.002064437,0.2062713,0.0001981819,0.0006175393,0.004252939,0.002299198,0.159355,0.578285,0.001050377,0.04402217,0.0002581495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949308,0.001370901,0.0008988668,0.0002289544,0.0000452922,0.00002011363,0.0009678116,0.000101179,0.001435896],"genre_scores_gemma":[0.984923,0.0007955056,0.003051998,0.0002000236,0.00001961896,0.00004129282,0.008651495,0.00005227235,0.00226478],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009429691,"threshold_uncertainty_score":0.01874959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004064075807606043,"score_gpt":0.2019141760202396,"score_spread":0.1978501002126336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}