{"id":"W2998100580","doi":"10.1002/jcph.1571","title":"Coexpression of Human Hepatic Uridine Diphosphate Glucuronosyltransferase Proteins: Implications for Ontogenetic Mechanisms and Isoform Coregulation","year":2019,"lang":"en","type":"article","venue":"The Journal of Clinical Pharmacology","topic":"Pharmacogenetics and Drug Metabolism","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Gene isoform; Ontogeny; Biology; Glucuronosyltransferase; Internal medicine; Endocrinology; Western blot; Blot; Uridine; Glucuronidation; Microsome; Genetics; Biochemistry; Medicine; Gene; Enzyme; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004431346,0.0002448565,0.0008205269,0.0001226757,0.0002253341,0.000008615517,0.0005257572,0.0002898381,0.000596151],"category_scores_gemma":[0.0001498878,0.000172355,0.0002912085,0.0001471417,0.00035757,0.0001209984,0.00008221711,0.0007552459,0.000008681526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002317242,"about_ca_system_score_gemma":0.0001914233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006984315,"about_ca_topic_score_gemma":0.000003530097,"domain_scores_codex":[0.9962957,0.001052797,0.001865358,0.0002319357,0.000179216,0.0003749904],"domain_scores_gemma":[0.9954346,0.002255475,0.001320104,0.0002140134,0.0004591143,0.0003167063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002697553,0.0006588965,0.006666827,0.0001221409,0.0004307844,0.000001675788,0.0002656774,0.00110451,0.9672751,0.001880979,0.001387852,0.01750799],"study_design_scores_gemma":[0.01948579,0.003785256,0.06180805,0.00006601952,0.00293664,0.000081579,0.0000798451,0.006520944,0.8536559,0.02522345,0.02595256,0.0004040001],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867937,0.002479168,0.003418905,0.00266158,0.00265853,0.001713998,0.00008677301,0.00001399583,0.0001733448],"genre_scores_gemma":[0.9933092,0.003167789,0.000740446,0.001949166,0.0006097569,0.00004599899,0.00001087486,0.00003294861,0.0001338075],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1136192,"threshold_uncertainty_score":0.7028433,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1620544192543954,"score_gpt":0.5110713937836602,"score_spread":0.3490169745292648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}