{"id":"W2998105939","doi":"10.3390/cells9010117","title":"Involvement of the Gap Junction Protein, Connexin43, in the Formation and Function of Invadopodia in the Human U251 Glioblastoma Cell Line","year":2020,"lang":"en","type":"article","venue":"Cells","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Ligue Contre le Cancer","keywords":"Invadopodia; Cortactin; Cell biology; Podosome; Extracellular matrix; Gap junction; Chemistry; Cell culture; Glioblastoma; Proto-oncogene tyrosine-protein kinase Src; Cell; Cancer research; Intracellular; Signal transduction; Biology; Cancer cell; Cytoskeleton; Cancer; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007739368,0.0002090182,0.0001797812,0.0002606798,0.0002783068,0.0002079126,0.00007226633,0.0001891008,0.0003060484],"category_scores_gemma":[0.00006518779,0.0001008007,0.0001635592,0.0001844517,0.0001512088,0.0001598173,0.0001016735,0.0002069579,0.0001394732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003628257,"about_ca_system_score_gemma":0.000294535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0053526,"about_ca_topic_score_gemma":0.005750994,"domain_scores_codex":[0.9999284,0.000008322962,0.00000706432,0.00001634063,0.00002177359,0.00001818204],"domain_scores_gemma":[0.9999726,0.000003080105,0.000007722145,0.000003666391,0.000004088539,0.000008813165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000550308,0.00001519167,0.0006377401,0.00003682587,0.000004889215,0.0001844174,0.00004661054,0.0000524604,0.9977468,0.0001667624,0.00003367207,0.001019537],"study_design_scores_gemma":[0.000009650043,0.0002324071,0.06627677,0.000009636948,0.00004335603,0.0008738808,0.0001393727,0.001077682,0.9270846,0.0001362419,0.004105016,0.00001142047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937177,0.003788862,0.001136631,0.00006968969,0.00001192658,0.00001363067,0.0002794489,0.00003659833,0.0009453753],"genre_scores_gemma":[0.9961475,0.001589403,0.000828537,0.00001866246,0.000002311454,0.00001683495,0.0002945888,0.000004071518,0.001098032],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0053526,"threshold_uncertainty_score":0.01064289,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01977753086767741,"score_gpt":0.2180506664828416,"score_spread":0.1982731356151642,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}